Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27970472 | 1.00 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1ACHENPC1KMT2A | |
| SCHEMBL23578669 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1NPC1KMT2AGAA | |
| SCHEMBL30782492 | 0.81 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1NPC1L3MBTL1 | |
| SCHEMBL17438862 | 0.81 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1NPC1EPHX2 | |
| SCHEMBL28087458 | 0.81 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1NPC1L3MBTL1 | |
| SCHEMBL20973539 | 0.81 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1NPC1EPHX2 | |
| SCHEMBL14434440 | 0.79 | ALDH1A1 (0.52) | ALDH1A1EPHX2 | |
| SCHEMBL4246046 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL12491777 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL4695720 | 0.78 | SMN1; SMN2 (0.31) | SMN1; SMN2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023243601-A1 | AZACYCLOALKYL CARBONYL CYCLIC AMINE COMPOUND | モジュラス株式会社 | 2023-12-21 | — | — | WO | disclosed |
| EP-3458449-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | Xenon Pharmaceuticals Inc. (CA) | 2019-03-27 | — | — | EP | disclosed |
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |