Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30782492 | 1.00 | SMN1; SMN2 (0.33) | SMN1; SMN2F10ALDH1A1NPC1MAPK1 | |
| SCHEMBL14800841 | 0.84 | F10 (0.35) | F10ALDH1A1NPC1NPSR1L3MBTL1 | |
| SCHEMBL30782507 | 0.81 | ACHE (0.32) | SMN1; SMN2ALDH1A1NPC1MAPK1NPSR1 | |
| SCHEMBL19617537 | 0.81 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1NPC1L3MBTL1 | |
| SCHEMBL27970472 | 0.81 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1NPC1L3MBTL1 | |
| SCHEMBL23578669 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL30782500 | 0.79 | GAA (0.32) | LMNA | |
| SCHEMBL20973539 | 0.78 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL17438862 | 0.78 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL30782478 | 0.76 | PTGS1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103249732-B | The bacterial topoisomerase II of suppression 2-ethyl carbamyl amino-1,3-benzothiazole-5-base | 生物区欧洲有限公司 | 2016-08-10 | — | — | CN | disclosed |