SCHEMBL19617577

SCHEMBL19617577

C=C(C)C(=O)NCCCOc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.71
MTNR1A P48039 1/20 0.64
MTNR1B P49286 1/20 0.64
RECQL P46063 3/20 0.63
HPGD P15428 3/20 0.57
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.55
NPC1 O15118 3/20 0.54
RAB9A P51151 3/20 0.54
HTR1B P28222 2/20 0.53
ALDH1A1 P00352 1/20 0.52
TAAR1 Q96RJ0 1/20 0.51
TSHR P16473 1/20 0.51
MAPT P10636 1/20 0.51
DRD2 P14416 1/20 0.50
DRD4 P21917 1/20 0.50
DRD3 P35462 1/20 0.50
HTR1D P28221 1/20 0.50
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10362456 0.95 L3MBTL1 (0.65) L3MBTL1MTNR1AMTNR1BRECQLHPGD
SCHEMBL698008 0.95 MTNR1A (0.71) L3MBTL1MTNR1AMTNR1BRECQLHPGD
SCHEMBL10362350 0.94 L3MBTL1 (0.63) L3MBTL1MTNR1AMTNR1BRECQLHPGD
SCHEMBL10364005 0.94 L3MBTL1 (0.63) L3MBTL1MTNR1AMTNR1BRECQLHPGD
SCHEMBL10362455 0.94 L3MBTL1 (0.63) L3MBTL1MTNR1AMTNR1BRECQLHPGD
SCHEMBL10362391 0.94 L3MBTL1 (0.63) L3MBTL1MTNR1AMTNR1BRECQLHPGD
SCHEMBL10362325 0.94 L3MBTL1 (0.63) L3MBTL1MTNR1AMTNR1BRECQLHPGD
SCHEMBL10362652 0.94 L3MBTL1 (0.63) L3MBTL1MTNR1AMTNR1BRECQLHPGD
SCHEMBL10364020 0.94 L3MBTL1 (0.63) L3MBTL1MTNR1AMTNR1BRECQLHPGD
SCHEMBL10363166 0.94 L3MBTL1 (0.63) L3MBTL1MTNR1AMTNR1BRECQLHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3458118-A1 HYDROPHOBIC INTRAOCULAR LENS Benz Research And Development Corporation (US) 2019-03-27 EP disclosed
WO-2017200934-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2017-11-23 WO disclosed