Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19261359 | 0.92 | POLB (0.49) | POLBTSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL179553 | 0.84 | POLB (0.53) | POLBTSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL19182655 | 0.82 | L3MBTL1 (0.48) | POLBTSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL21016171 | 0.81 | POLB (0.50) | POLBTSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL19200801 | 0.80 | L3MBTL1 (0.43) | POLBTSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL23771011 | 0.79 | POLB (0.49) | POLBTSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL20049915 | 0.79 | POLB (0.49) | POLBTSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL23771148 | 0.79 | POLB (0.49) | POLBTSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL21016165 | 0.78 | FKBP1A (0.48) | POLBTSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL20340664 | 0.78 | POLB (0.47) | POLBTSHRLMNAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822131-B2 | Certain chemical entities, compositions and methods | INTELLIKINE LLC (US) | 2017-11-21 | — | — | US | disclosed |