Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 2/20 | 0.56 |
| ▸ | HRH1 | P35367 | 2/20 | 0.56 |
| ▸ | GNAI3 | P08754 | 8/20 | 0.56 |
| ▸ | GNAI1 | P63096 | 8/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GNAO1 | P09471 | 7/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25887674 | 1.00 | HRH2 (0.56) | HRH2HRH1GNAI3GNAI1L3MBTL1 | |
| SCHEMBL25887670 | 1.00 | HRH2 (0.56) | HRH2HRH1GNAI3GNAI1L3MBTL1 | |
| SCHEMBL31632752 | 0.93 | GNAI3 (0.65) | HRH2HRH1GNAI3GNAI1L3MBTL1 | |
| SCHEMBL31632758 | 0.93 | GNAI3 (0.65) | HRH2HRH1GNAI3GNAI1L3MBTL1 | |
| SCHEMBL10070849 | 0.93 | GNAI3 (0.60) | HRH2HRH1GNAI3GNAI1L3MBTL1 | |
| SCHEMBL17167936 | 0.89 | GNAI3 (0.65) | HRH2HRH1GNAI3GNAI1L3MBTL1 | |
| SCHEMBL25887672 | 0.88 | L3MBTL1 (0.54) | HRH2HRH1GNAI3GNAI1L3MBTL1 | |
| SCHEMBL29129462 | 0.88 | GNAI3 (0.51) | HRH2HRH1GNAI3GNAI1L3MBTL1 | |
| SCHEMBL4685663 | 0.88 | HRH2 (0.49) | HRH2HRH1GNAI3GNAI1L3MBTL1 | |
| SCHEMBL4685669 | 0.88 | HRH2 (0.49) | HRH2HRH1GNAI3GNAI1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822083-B2 | Amphiphilic derivatives of triazamacrocyclic compounds, products and compositions including same, and synthesis methods and uses thereof | BIOCELLCHALLENGE (FR) | 2017-11-21 | — | — | US | disclosed |