SCHEMBL19618591

SCHEMBL19618591

c1cc(-c2ccnc3ccccc23)cc(-c2cc(-c3ccc4ccccc4c3)nc3ccc(-c4cc5ccccc5c5ccccc45)cc23)c1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACVR1 Q04771 7/20 0.47
PIK3CA P42336 2/20 0.46
ACACA Q13085 4/20 0.43
ERN1 O75460 1/20 0.40
MET P08581 1/20 0.40
AAK1 Q2M2I8 1/20 0.39
CYP11B1 P15538 1/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19618588 0.95 ACVR1 (0.49) ACVR1PIK3CAACACAERN1AAK1
SCHEMBL19618285 0.94 PIK3CA (0.52) ACVR1PIK3CAACACAERN1MET
SCHEMBL19618451 0.91 ACVR1 (0.50) ACVR1PIK3CAACACAAAK1CYP11B1
SCHEMBL19618279 0.88 PIK3CA (0.56) ACVR1PIK3CAACACAAAK1MEN1
SCHEMBL19618587 0.88 ACVR1 (0.42) ACVR1PIK3CAACACAERN1CYP11B1
SCHEMBL19618468 0.87 PIK3CA (0.60) ACVR1PIK3CAACACAMEN1KMT2A
SCHEMBL19618584 0.86 DHODH (0.44) PIK3CAACACACYP11B1CYP1A1CYP1B1
SCHEMBL19618580 0.86 ACACA (0.43) ACACACYP11B1CYP1A1CYP1B1MEN1
SCHEMBL19618437 0.86 PIK3CA (0.52) ACVR1PIK3CAACACAAAK1CYP11B1
SCHEMBL19618397 0.85 PIK3CA (0.64) ACVR1PIK3CAACACAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9825242-B2 Compound for organic optoelectric device, organic light-emitting diode including same, display device including organic light-emitting diode CHEIL INDUSTRIES, INC. (KR) 2017-11-21 US disclosed
US-9825242-B2 Compound for organic optoelectric device, organic light-emitting diode including same, display device including organic light-emitting diode CHEIL INDUSTRIES, INC. (KR) 2017-11-21 US disclosed