Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
| ▸ | GSTA1 | P08263 | 2/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19618691 | 0.84 | LPAR2 (0.38) | LPAR3LPAR2LPAR1S1PR2S1PR1 | |
| SCHEMBL20023898 | 0.83 | LPAR2 (0.36) | ESR1LPAR3LPAR2LPAR1S1PR2 | |
| SCHEMBL19912235 | 0.82 | LPAR2 (0.35) | LPAR3LPAR2LPAR1S1PR2S1PR1 | |
| SCHEMBL11648341 | 0.79 | LPAR3 (0.38) | ESR1LPAR3LPAR2LPAR1S1PR2 | |
| SCHEMBL11690877 | 0.78 | ESR1 (0.42) | ESR1LPAR3LPAR2LPAR1S1PR2 | |
| SCHEMBL11533263 | 0.75 | ESR1 (0.45) | ESR1LPAR3LPAR2LPAR1S1PR2 | |
| SCHEMBL28530427 | 0.74 | HSPA5 (0.48) | ESR1LPAR3LPAR2LPAR1 | |
| SCHEMBL20023899 | 0.74 | THRA (0.41) | LPAR3LPAR2LPAR1S1PR2S1PR1 | |
| SCHEMBL11594658 | 0.73 | THRA (0.44) | ESR1LPAR3LPAR2LPAR1S1PR2 | |
| SCHEMBL10988240 | 0.73 | ESR1 (0.49) | ESR1LPAR2S1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180094121-A1 | LIGHT REFLECTIVE PARTS AND REFLECTIVE PARTS FOR AUTOMOBILE LAMP | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2018-04-05 | — | — | US | disclosed |
| US-20180094102-A1 | FLAME-RETARDANT RESIN COMPOSITION | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2018-04-05 | — | — | US | disclosed |
| US-20180057685-A1 | FLAME-RETARDANT RESIN COMPOSITION | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2018-03-01 | — | — | US | disclosed |
| US-9822240-B1 | Light reflective parts and reflective parts for automobile lamp | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2017-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180057685-A1 | FLAME-RETARDANT RESIN COMPOSITION | PRPF4, RPL4, PSMB4 | ESR1 1837/4885LPAR3 2183/4885LPAR2 2015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.