SCHEMBL19618945

SCHEMBL19618945

CCOC(O)/C=C/c1ccc(C)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
PTGS2 P35354 3/20 0.42
PTGS1 P23219 2/20 0.42
ALOX5 P09917 1/20 0.42
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41
MAOB P27338 1/20 0.41
CA1 P00915 2/20 0.40
RELA Q04206 1/20 0.40
TUBB4A P04350 1/20 0.39
TUBB P07437 1/20 0.39
TUBA3C P0DPH7 1/20 0.39
TUBA1B P68363 1/20 0.39
TUBA4A P68366 1/20 0.39
TUBB4B P68371 1/20 0.39
TUBB3 Q13509 1/20 0.39
TUBB2A Q13885 1/20 0.39
TUBB8 Q3ZCM7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7923406 0.84 MEN1 (0.49) CYP3A4PTGS2BCHEACHEMAOB
SCHEMBL7923413 0.84 MEN1 (0.49) CYP3A4PTGS2BCHEACHEMAOB
SCHEMBL6449282 0.76 CYP3A4 (0.55) CYP3A4CYP2C9CYP2C19PTGS2PTGS1
SCHEMBL6449288 0.76 CYP3A4 (0.55) CYP3A4CYP2C9CYP2C19PTGS2PTGS1
SCHEMBL21841016 0.75 LCK (0.55) CYP2C19PTGS2PTGS1MAOBRELA
SCHEMBL16865348 0.73 CYP2C9 (0.45) CYP3A4CYP2C9CYP2C19PTGS2BCHE
SCHEMBL16865352 0.73 CYP2C9 (0.45) CYP3A4CYP2C9CYP2C19PTGS2BCHE
SCHEMBL31376558 0.73 CYP2C9 (0.45) CYP3A4CYP2C9CYP2C19PTGS2BCHE
SCHEMBL12241652 0.72 CYP3A4 (0.60) CYP3A4CYP2C9CYP2C19PTGS2PTGS1
SCHEMBL28847935 0.72 CYP3A4 (0.60) CYP3A4CYP2C9CYP2C19PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9822123-B2 De novo synthesis of bacteriochlorins NORTH CAROLINA STATE UNIVERSITY (US) 2017-11-21 US disclosed