SCHEMBL19619044

SCHEMBL19619044

CCOP(=O)(CO[C@@H]1CCC(n2cc(C)c(=O)[nH]c2=O)C1)OCC

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TK1 P04183 4/20 0.47
TYMP P19971 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23315125 0.86 TK1 (0.49) TK1TYMP
SCHEMBL8662401 0.79 TK1 (0.47) TK1TYMP
SCHEMBL8714093 0.78 TK1 (0.56) TK1
SCHEMBL19619045 0.78 TK1 (0.51) TK1
SCHEMBL17157340 0.77 TK1 (0.41) TK1
SCHEMBL17174567 0.77 TK1 (0.42) TK1TYMP
SCHEMBL17174566 0.76 TK1 (0.46) TK1TYMP
SCHEMBL12154746 0.76 TK1 (0.80) TK1
SCHEMBL12154745 0.76 TK1 (0.61) TK1
SCHEMBL8708572 0.76 TK1 (0.80) TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9822137-B2 Phosphonucleosides useful in the treatment of viral disorders UNIVERSITY COLLEGE CORK (IE) 2017-11-21 US disclosed