Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9148964 | 0.85 | TK1 (0.50) | TK1POLBTYMP | |
| SCHEMBL8663377 | 0.85 | TK1 (0.50) | TK1POLBTYMP | |
| SCHEMBL9150261 | 0.80 | TK1 (0.45) | TK1POLBALDH1A1LMNAALB | |
| SCHEMBL19619044 | 0.79 | TK1 (0.47) | TK1TYMP | |
| SCHEMBL17157431 | 0.79 | TK1 (0.42) | TK1POLBTYMP | |
| SCHEMBL17157351 | 0.79 | TK1 (0.42) | TK1POLBALDH1A1LMNAALB | |
| SCHEMBL9150434 | 0.77 | TK1 (0.45) | TK1POLBALDH1A1LMNAALB | |
| SCHEMBL12154713 | 0.77 | POLB (0.54) | TK1POLBALDH1A1LMNAALB | |
| SCHEMBL12154611 | 0.77 | POLB (0.54) | TK1POLBALDH1A1LMNAALB | |
| SCHEMBL8714093 | 0.75 | TK1 (0.56) | TK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744600-A | VIRICIDES, ANTITUMOR AGENTS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-04-28 | — | — | US | disclosed |