Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 6/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1961917 | 1.00 | CYP3A4 (0.51) | CYP3A4CYP2D6DGAT1NAMPTMAPT | |
| SCHEMBL1038543 | 0.92 | CYP3A4 (0.51) | CYP3A4CYP2D6MAPTFAAHTHRB | |
| SCHEMBL1038541 | 0.92 | CYP3A4 (0.51) | CYP3A4CYP2D6MAPTFAAHTHRB | |
| SCHEMBL1076089 | 0.91 | CYP3A4 (0.50) | CYP3A4CYP2D6NAMPTMAPTFAAH | |
| SCHEMBL1076091 | 0.91 | CYP3A4 (0.50) | CYP3A4CYP2D6NAMPTMAPTFAAH | |
| SCHEMBL1076482 | 0.91 | CYP2D6 (0.54) | CYP3A4CYP2D6DGAT1NAMPTHTT | |
| SCHEMBL1076479 | 0.91 | CYP2D6 (0.54) | CYP3A4CYP2D6DGAT1NAMPTHTT | |
| SCHEMBL1035752 | 0.91 | CYP3A4 (0.51) | CYP3A4CYP2D6DGAT1NAMPTFAAH | |
| SCHEMBL1035753 | 0.91 | CYP3A4 (0.51) | CYP3A4CYP2D6DGAT1NAMPTFAAH | |
| SCHEMBL1075689 | 0.91 | CYP3A4 (0.46) | CYP3A4CYP2D6DGAT1NAMPTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110144159-A1 | ETHER BENZYLIDENE PIPERIDINE ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS | PFIZER INC | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144159-A1 | ETHER BENZYLIDENE PIPERIDINE ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS | FAAH, FAAH2, PAH | CYP3A4 329/4885CYP2D6 382/4885DGAT1 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.