Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16556818 | 0.92 | LMNA (0.40) | LMNAL3MBTL1TDP1ALDH1A1KDM4E | |
| SCHEMBL14432954 | 0.92 | LMNA (0.40) | LMNAL3MBTL1TDP1ALDH1A1KDM4E | |
| SCHEMBL7151040 | 0.81 | LMNA (0.44) | LMNAL3MBTL1TDP1ALDH1A1THRB | |
| SCHEMBL7595607 | 0.81 | LMNA (0.44) | LMNAL3MBTL1TDP1ALDH1A1THRB | |
| SCHEMBL7150167 | 0.81 | LMNA (0.44) | LMNAL3MBTL1TDP1ALDH1A1THRB | |
| SCHEMBL5919483 | 0.81 | LMNA (0.44) | LMNAL3MBTL1TDP1ALDH1A1THRB | |
| SCHEMBL7151383 | 0.81 | LMNA (0.44) | LMNAL3MBTL1TDP1ALDH1A1THRB | |
| SCHEMBL3223716 | 0.81 | LMNA (0.44) | LMNAL3MBTL1TDP1ALDH1A1THRB | |
| SCHEMBL30698046 | 0.81 | LMNA (0.50) | LMNAL3MBTL1TDP1ALDH1A1KDM4E | |
| Sorbitol SCHEMBL8212144 | 0.80 | LMNA (0.55) | LMNAL3MBTL1TDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822186-B2 | Bispecific antibodies that bind to CD38 and CD3 | XENCOR, INC. (US) | 2017-11-21 | — | — | US | disclosed |