SCHEMBL3223716

SCHEMBL3223716

C[C@@H](O)[C@H](O)C[C@@H](O)CO

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.44
ALDH1A1 P00352 1/20 0.44
TDP1 Q9NUW8 2/20 0.42
TSHR P16473 1/20 0.37
THRB P10828 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.33
USP2 O75604 1/20 0.31
CYP3A4 P08684 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7151383 1.00 LMNA (0.44) LMNAALDH1A1TDP1TSHRTHRB
SCHEMBL7150167 1.00 LMNA (0.44) LMNAALDH1A1TDP1TSHRTHRB
SCHEMBL7151040 1.00 LMNA (0.44) LMNAALDH1A1TDP1TSHRTHRB
SCHEMBL7595607 1.00 LMNA (0.44) LMNAALDH1A1TDP1TSHRTHRB
SCHEMBL5919483 1.00 LMNA (0.44) LMNAALDH1A1TDP1TSHRTHRB
Propylene Glycol SCHEMBL4753423 0.95 TDP1 (0.53) LMNAALDH1A1TDP1TSHRTHRB
SCHEMBL16556818 0.83 LMNA (0.40) LMNAALDH1A1TDP1TSHRTHRB
SCHEMBL14432954 0.83 LMNA (0.40) LMNAALDH1A1TDP1TSHRTHRB
SCHEMBL31544633 0.82 LMNA (0.44) LMNAALDH1A1TDP1TSHRTHRB
SCHEMBL19619947 0.81 LMNA (0.41) LMNAALDH1A1TDP1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-9616139-B2 Conjugating amines THE GENERAL HOSPITAL CORPORATION (US) 2017-04-11 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed
US-20150031863-A1 CONJUGATING AMINES THE GENERAL HOSPITAL CORPORATION (US) 2015-01-29 US disclosed
WO-2013009826-A9 CONJUGATING AMINES THE GENERAL HOSPITAL CORPORATION (US) 2013-03-21 WO disclosed
WO-2013009826-A1 CONJUGATING AMINES THE GENERAL HOSPITAL CORPORATION (US) 2013-01-17 WO disclosed
US-5686256-A TYVELOSE-CONTAINING DISACCHARIDE OR OLIGOSACCHARIDE BINDS WITH ANTIBODY TO FORM COMPLEX COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1997-11-11 US disclosed
EP-0682527-A4 CARBOHYDRATE-BASED VACCINE AND DIAGNOSTIC REAGENT FOR TRICHINOSIS. UNIV COLORADO STATE RES FOUND (US) 1997-05-21 EP disclosed
EP-0729648-A4 STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS UNISEARCH LTD (AU) 1997-01-02 EP disclosed
WO-1996035239-A1 HIGH ENERGY DENSITY VANADIUM ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND ALL-VANADIUM REDOX CELLS AND BATTERIES CONTAINING HIGH ENERGY VANADIUM ELECTROLYTE SOLUTIONS UNISEARCH LIMITED (AU) 1996-11-07 WO disclosed
WO-1996030044-A1 CARBOHYDRATE-BASED VACCINE AND DIAGNOSTIC REAGENT FOR TRICHINOSIS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1996-10-03 WO disclosed
EP-0729648-A1 STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS UNISEARCH LIMITED (AU) 1996-09-04 EP disclosed
US-5541075-A DISACCHARIDES, OLIGOSACCHARIDES HESKA CORPORATION (US) 1996-07-30 US disclosed
EP-0682527-A1 CARBOHYDRATE-BASED VACCINE AND DIAGNOSTIC REAGENT FOR TRICHINOSIS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1995-11-22 EP disclosed
WO-1995012219-A1 STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS UNISEARCH LIMITED (AU) 1995-05-04 WO disclosed
WO-1994017824-A1 CARBOHYDRATE-BASED VACCINE AND DIAGNOSTIC REAGENT FOR TRICHINOSIS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1994-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150031863-A1 CONJUGATING AMINES CD47, CD58, CD44 LMNA 2936/4885ALDH1A1 3665/4885TDP1 1021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.