Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19846628 | 1.00 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL29417881 | 1.00 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL11700557 | 0.91 | TSHR (0.52) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL11700563 | 0.91 | TSHR (0.52) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL2829746 | 0.89 | TSHR (0.45) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL5586275 | 0.89 | TSHR (0.50) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL7718104 | 0.89 | TSHR (0.45) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL2606268 | 0.89 | TSHR (0.45) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL2829742 | 0.89 | TSHR (0.45) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL10608809 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110366703-B | Substrate pretreatment composition for nanoimprint lithography | 佳能株式会社 | 2023-11-14 | — | — | CN | disclosed |
| CN-111708260-B | Substrate pretreatment to reduce fill time in nanoimprint lithography | 佳能株式会社 | 2023-11-10 | — | — | CN | disclosed |
| EP-4097155-A1 | ACTINICALLY-CROSSLINKABLE POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF | Clearlab SG Pte Ltd (SG) | 2022-12-07 | — | — | EP | disclosed |
| EP-3359119-B1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2021-12-29 | — | — | EP | disclosed |
| US-11000454-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2021-05-11 | — | — | US | disclosed |
| US-20190117523-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2019-04-25 | — | — | US | disclosed |
| US-20180037688-A1 | CURABLE COMPOSITION FOR IMPRINTS, CURED PRODUCT, PATTERN FORMING METHOD, LITHOGRAPHY METHOD, PATTERN AND LITHOGRAPHY MASK | FUJIFILM CORPORATION (JP) | 2018-02-08 | — | — | US | disclosed |
| WO-2017198840-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2017-11-23 | — | — | WO | disclosed |
| EP-3246001-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GmbH (DE) | 2017-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11000454-B2 | Dental composition | PPIP5K2, INPP5D, DCPS | TSHR 4113/4885ALDH1A1 1990/4885TP53 2225/4885 |
| US-20190117523-A1 | DENTAL COMPOSITION | PPIP5K2, INPP5D, DCPS | TSHR 4113/4885ALDH1A1 1990/4885TP53 2225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.