Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 8/20 | 0.38 |
| ▸ | ADK | P55263 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | FADS1 | O60427 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19620490 | 0.94 | ADK (0.38) | ADKMAPTKDM4EPOLBRAB9A | |
| SCHEMBL19620607 | 0.90 | KDM4E (0.33) | MDM2ADKMAPTKDM4EPOLB | |
| SCHEMBL19620522 | 0.90 | KDM4E (0.42) | MDM2ADKMAPTKDM4EPOLB | |
| SCHEMBL19620542 | 0.90 | POLB (0.42) | ADKMAPTKDM4EPOLBGSK3B | |
| SCHEMBL19620642 | 0.89 | ADK (0.38) | ADKMAPTKDM4EPOLB | |
| SCHEMBL19620605 | 0.89 | CNR1 (0.35) | MDM2ADKMAPTKDM4EPOLB | |
| SCHEMBL19620548 | 0.89 | MEN1 (0.40) | ADKMAPTKDM4EPOLBTP53 | |
| SCHEMBL19620634 | 0.88 | MDM2 (0.35) | MDM2MAPTKDM4EPOLBRAB9A | |
| SCHEMBL19620342 | 0.86 | MDM2 (0.36) | MDM2ADKMAPTKDM4EPOLB | |
| SCHEMBL19620660 | 0.86 | PSEN1 (0.35) | MAPTKDM4EPOLBFADS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2897607-B1 | INHIBITORS OF BETA-HYDROLASE FOR TREATMENT OF CANCER | RHODE ISLAND HOSPITAL (US) | 2017-11-22 | — | — | EP | disclosed |