Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19620689 | 0.92 | KDM4E (0.38) | KDM4EPOLBMAPT | |
| SCHEMBL19620570 | 0.86 | MAPT (0.39) | KDM4EPOLBMAPT | |
| SCHEMBL22902049 | 0.86 | MAPT (0.39) | KDM4EPOLBMAPT | |
| SCHEMBL19620522 | 0.84 | KDM4E (0.42) | KDM4EPOLBMAPT | |
| SCHEMBL19620675 | 0.84 | MAPT (0.42) | KDM4EPOLBMAPT | |
| SCHEMBL19620603 | 0.83 | POLB (0.50) | KDM4EPOLBMAPT | |
| SCHEMBL19620492 | 0.81 | KDM4E (0.36) | KDM4EPOLBMAPT | |
| SCHEMBL19620577 | 0.81 | EGFR (0.37) | KDM4EPOLBMAPT | |
| SCHEMBL19620548 | 0.81 | MEN1 (0.40) | KDM4EPOLBMAPT | |
| SCHEMBL19620654 | 0.81 | KDM4E (0.38) | KDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2897607-B1 | INHIBITORS OF BETA-HYDROLASE FOR TREATMENT OF CANCER | RHODE ISLAND HOSPITAL (US) | 2017-11-22 | — | — | EP | disclosed |