Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14066500 | 1.00 | KDM4E (0.49) | KDM4EHPGDHTTMAPTLMNA | |
| SCHEMBL19621099 | 0.91 | KDM4E (0.46) | KDM4EHPGDHTTMAPTLMNA | |
| SCHEMBL19621071 | 0.90 | KDM4E (0.47) | KDM4EHPGDHTTMAPTLMNA | |
| SCHEMBL2735115 | 0.89 | KDM4E (0.50) | KDM4EHPGDHTTMAPTLMNA | |
| SCHEMBL31346592 | 0.89 | KDM4E (0.50) | KDM4EHPGDHTTMAPTLMNA | |
| SCHEMBL514041 | 0.89 | KDM4E (0.50) | KDM4EHPGDHTTMAPTLMNA | |
| SCHEMBL29350853 | 0.89 | KDM4E (0.50) | KDM4EHPGDHTTMAPTLMNA | |
| SCHEMBL1087112 | 0.89 | KDM4E (0.50) | KDM4EHPGDHTTMAPTLMNA | |
| SCHEMBL20022365 | 0.89 | KDM4E (0.51) | KDM4EHPGDHTTMAPTLMNA | |
| SCHEMBL19621080 | 0.89 | KDM4E (0.51) | KDM4EHPGDHTTMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11236271-B2 | Liquid-crystal media and light modulation element | MERCK PATENT GMBH (DE) | 2022-02-01 | — | — | US | disclosed |
| EP-3510122-B1 | LIQUID-CRYSTAL MEDIA AND LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2020-12-16 | — | — | EP | disclosed |
| US-10358600-B2 | Polymerisable liquid crystal material and polymerised liquid crystal film | MERCK PATENT GMBH (DE) | 2019-07-23 | — | — | US | disclosed |
| US-20190185746-A1 | LIQUID-CRYSTAL MEDIA AND LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2019-06-20 | — | — | US | disclosed |
| EP-3246378-B1 | POLYMERISABLE LIQUID CRYSTAL MATERIAL AND POLYMERISED LIQUID CRYSTAL FILM | MERCK PATENT GMBH (DE) | 2019-03-20 | — | — | EP | disclosed |
| WO-2018046421-A1 | LIQUID-CRYSTAL MEDIA AND LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2018-03-15 | — | — | WO | disclosed |
| US-20170335192-A1 | Polymerisable Liquid Crystal Material and Polymerised Liquid Crystal Film | MERCK PATENT GMBH (DE) | 2017-11-23 | — | — | US | disclosed |
| US-20170335192-A1 | Polymerisable Liquid Crystal Material and Polymerised Liquid Crystal Film | MERCK PATENT GMBH (DE) | 2017-11-23 | — | — | US | disclosed |
| EP-3246378-A1 | POLYMERISABLE LIQUID CRYSTAL MATERIAL AND POLYMERISED LIQUID CRYSTAL FILM | Merck Patent GmbH (DE) | 2017-11-22 | — | — | EP | disclosed |