SCHEMBL2735115

SCHEMBL2735115

CCn1c2ccc(C(=O)c3ccccc3C)cc2c2cc(/C(C)=N\OC(C)=O)ccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.50
LMNA P02545 5/20 0.50
MAPT P10636 5/20 0.50
HPGD P15428 4/20 0.49
HTT P42858 4/20 0.49
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
ALDH1A1 P00352 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
GFER P55789 1/20 0.39
MAPK1 P28482 3/20 0.39
POLB P06746 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
CNR2 P34972 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
BLM P54132 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38
TUBA3C P0DPH7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1087112 1.00 KDM4E (0.50) KDM4ELMNAMAPTHPGDHTT
SCHEMBL31346592 1.00 KDM4E (0.50) KDM4ELMNAMAPTHPGDHTT
SCHEMBL514041 1.00 KDM4E (0.50) KDM4ELMNAMAPTHPGDHTT
SCHEMBL29350853 1.00 KDM4E (0.50) KDM4ELMNAMAPTHPGDHTT
SCHEMBL29056369 0.97 MAPT (0.47) KDM4ELMNAMAPTHPGDHTT
SCHEMBL30355181 0.94 KDM4E (0.47) KDM4ELMNAMAPTHPGDHTT
SCHEMBL29557410 0.92 KDM4E (0.43) KDM4ELMNAMAPTHPGDHTT
SCHEMBL23346983 0.92 HPGD (0.51) KDM4ELMNAMAPTHPGDHTT
SCHEMBL15996476 0.92 KDM4E (0.48) KDM4ELMNAMAPTHPGDHTT
SCHEMBL25629805 0.92 KDM4E (0.48) KDM4ELMNAMAPTHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026219-A1 LIGHT-EMITTING PARTICLES AND METHOD FOR PRODUCING THE SAME, LIGHT-EMITTING PARTICLE DISPERSION, LIGHT CONVERSION FILM, LAMINATE, LIGHT CONVERSION LAYER, COLOR FILTER, AND LIGHT-EMITTING ELEMENT DIC CORPORATION (JP) 2024-01-25 US disclosed
US-20240026219-A1 LIGHT-EMITTING PARTICLES AND METHOD FOR PRODUCING THE SAME, LIGHT-EMITTING PARTICLE DISPERSION, LIGHT CONVERSION FILM, LAMINATE, LIGHT CONVERSION LAYER, COLOR FILTER, AND LIGHT-EMITTING ELEMENT DIC CORPORATION (JP) 2024-01-25 US disclosed
EP-4249569-A1 LUMINESCENT PARTICLES AND PRODUCTION METHOD THEREFOR, LUMINESCENT-PARTICLE DISPERSION, PHOTOCONVERSION FILM, LAYERED PRODUCT, PHOTOCONVERSION LAYER, COLOR FILTER, AND LUMINESCENT ELEMENT DIC Corporation (JP) 2023-09-27 EP disclosed
US-11667804-B2 Photocurable transparent ink composition for three-dimensional molding and preparation method and application thereof ZHUHAI SAILNER 3D TECHNOLOGY CO., LTD. (CN) 2023-06-06 US disclosed
US-11656384-B2 Composition, film, lens, solid state imaging element, and compounds FUJIFILM CORPORATION (JP) 2023-05-23 US disclosed
US-11656384-B2 Composition, film, lens, solid state imaging element, and compounds FUJIFILM CORPORATION (JP) 2023-05-23 US disclosed
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-05-11 US disclosed
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-05-11 US disclosed
US-20230131561-A1 COLORING COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-04-27 US disclosed
US-20230131561-A1 COLORING COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-04-27 US disclosed
US-20150210797-A1 SILICON-CONTAINING HIGHLY BRANCHED POLYMER AND CURABLE COMPOSITION CONTAINING THE SAME NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-07-30 US disclosed
EP-2878608-A1 SILICON-CONTAINING HYPERBRANCHED POLYMER AND CURABLE COMPOSITION CONTAINING SAME Nissan Chemical Industries, Ltd. (JP) 2015-06-03 EP disclosed
US-8586268-B2 Oxime ester photoinitiators BASF SE (DE) 2013-11-19 US disclosed
EP-2647673-A1 CURABLE COMPOSITION FOR COATING CONTAINING FLUORINE-CONTAINING HYPERBRANCHED POLYMER Nissan Chemical Industries, Ltd. (JP) 2013-10-09 EP disclosed
US-8088836-B2 Oxime ester compounds and photosensitive resin compositions using the same NIPPON CHEMICAL WORKS CO., LTD. (JP) 2012-01-03 US disclosed
US-8088836-B2 Oxime ester compounds and photosensitive resin compositions using the same NIPPON CHEMICAL WORKS CO., LTD. (JP) 2012-01-03 US disclosed
US-20100210749-A1 Oxime ester compounds and photosensitive resin compositions using the same NIPPON CHEMICAL WORKS CO., LTD. 2010-08-19 US disclosed
US-20100210749-A1 Oxime ester compounds and photosensitive resin compositions using the same NIPPON CHEMICAL WORKS CO., LTD. 2010-08-19 US disclosed
US-20100188765-A1 Oxime Ester Photoinitiators CIBA CORPORATION 2010-07-29 US disclosed
US-20100188765-A1 Oxime Ester Photoinitiators CIBA CORPORATION 2010-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100210749-A1 Oxime ester compounds and photosensitive resin compositions using the same PPOX, FTO, NR2E3 KDM4E 42/4885LMNA 4150/4885MAPT 1568/4885
US-11656384-B2 Composition, film, lens, solid state imaging element, and compounds UACA, F12, ERGIC1 KDM4E 2809/4885LMNA 503/4885MAPT 1060/4885
US-20100188765-A1 Oxime Ester Photoinitiators NR2E3, CYP3A4, CHRM4 KDM4E 856/4885LMNA 4696/4885MAPT 4211/4885
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS OCIAD1, OCIAD2, OXER1 KDM4E 1857/4885LMNA 3831/4885MAPT 579/4885
US-20230131561-A1 COLORING COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT AND IMAGE DISPLAY DEVICE SF1, SPIN1, RER1 KDM4E 3761/4885LMNA 2695/4885MAPT 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.