Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14748472 | 0.87 | UCHL1 (0.33) | UCHL1 | |
| SCHEMBL7862645 | 0.86 | PDE4A (0.38) | UCHL1 | |
| SCHEMBL7862660 | 0.86 | UCHL1 (0.39) | UCHL1 | |
| SCHEMBL7864997 | 0.85 | CXCR2 (0.39) | UCHL1 | |
| SCHEMBL7865496 | 0.85 | PDE4A (0.38) | UCHL1 | |
| SCHEMBL19622208 | 0.84 | — | — | |
| SCHEMBL7857433 | 0.83 | PDE4A (0.36) | — | |
| SCHEMBL7857229 | 0.82 | LIPE (0.41) | — | |
| SCHEMBL19622219 | 0.82 | CXCR2 (0.32) | — | |
| SCHEMBL19622321 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246034-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | Anacor Pharmaceuticals, Inc. (US) | 2017-11-22 | — | — | EP | disclosed |