Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 3/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 13/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19622248 | 0.83 | PDE4B (0.44) | ARPDE4BSLC22A12 | |
| SCHEMBL7997145 | 0.77 | AR (0.45) | ARPGRPDE4BSLC22A12TRPV4 | |
| SCHEMBL4181007 | 0.77 | AR (0.50) | ARPGRPDE4BSLC22A12TRPV4 | |
| SCHEMBL2526722 | 0.75 | PDE4B (0.79) | PDE4B | |
| SCHEMBL8543199 | 0.75 | AR (0.62) | ARPGRSLC22A12TRPV4 | |
| SCHEMBL4184922 | 0.73 | AR (0.65) | ARPGRSLC22A12TRPV4 | |
| SCHEMBL13890483 | 0.73 | AR (0.56) | ARPGRPDE4BSLC22A12TRPV4 | |
| SCHEMBL1656135 | 0.72 | PDE4B (0.51) | ARPDE4B | |
| SCHEMBL474005 | 0.72 | AR (0.68) | ARPGRSLC22A12TRPV4 | |
| SCHEMBL4171343 | 0.72 | AR (0.59) | ARPGRSLC22A12TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246034-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | Anacor Pharmaceuticals, Inc. (US) | 2017-11-22 | — | — | EP | disclosed |