Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19804025 | 0.88 | THRB (0.40) | MTNR1AMTNR1BTHRBPTGER4POLB | |
| SCHEMBL19796458 | 0.83 | THRB (0.38) | MTNR1AMTNR1BTHRBPTGER4POLB | |
| SCHEMBL19804283 | 0.81 | MTNR1A (0.47) | MTNR1AMTNR1BTHRBPTGER4ERN1 | |
| SCHEMBL19804617 | 0.80 | EGFR (0.38) | MTNR1AMTNR1BPTGER4POLBAPEX1 | |
| SCHEMBL19801688 | 0.80 | EGFR (0.38) | MTNR1AMTNR1BPTGER4POLBAPEX1 | |
| SCHEMBL19804169 | 0.80 | CA1 (0.37) | MTNR1AMTNR1BTHRBPTGER4POLB | |
| SCHEMBL19804322 | 0.80 | THRB (0.39) | THRBPTGER4POLBAPEX1HTT | |
| SCHEMBL19804224 | 0.78 | PTGER4 (0.40) | MTNR1AMTNR1BPTGER4ERN1BAZ2B | |
| SCHEMBL19624352 | 0.77 | CA1 (0.39) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL19804207 | 0.77 | TSHR (0.37) | MTNR1AMTNR1BTHRBPTGER4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246305-A1 | COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC Corporation (JP) | 2017-11-22 | — | — | EP | disclosed |