Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | TRPA1 | O75762 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | ICMT | O60725 | 4/20 | 0.60 |
| ▸ | FNTA | P49354 | 5/20 | 0.54 |
| ▸ | FNTB | P49356 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Farnesylthioacetic Acid SCHEMBL7775705 | 1.00 | MAPT (1.00) | MAPTKMT2ATRPA1MEN1ALDH1A1 | |
| SCHEMBL14660861 | 0.98 | MAPT (0.97) | MAPTKMT2ATRPA1MEN1ALDH1A1 | |
| SCHEMBL12793914 | 0.88 | MAPT (0.79) | MAPTKMT2ATRPA1MEN1ALDH1A1 | |
| SCHEMBL3409241 | 0.88 | MAPT (0.79) | MAPTKMT2ATRPA1MEN1ALDH1A1 | |
| SCHEMBL14672118 | 0.88 | MAPT (0.78) | MAPTKMT2ATRPA1MEN1ALDH1A1 | |
| SCHEMBL14672111 | 0.86 | MAPT (0.76) | MAPTKMT2ATRPA1MEN1ALDH1A1 | |
| SCHEMBL7771964 | 0.85 | MAPT (0.73) | MAPTKMT2ATRPA1MEN1ALDH1A1 | |
| SCHEMBL3710993 | 0.85 | MAPT (0.73) | MAPTKMT2ATRPA1MEN1ALDH1A1 | |
| SCHEMBL4032129 | 0.84 | MAPT (0.72) | MAPTKMT2ATRPA1MEN1ALDH1A1 | |
| SCHEMBL2879944 | 0.83 | ICMT (0.75) | MAPTKMT2ATRPA1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011067346-A1 | METHOD FOR DETERMINING THE EFFICIENCY OF A CANCER TREATMENT | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-06-09 | — | — | WO | disclosed |