Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | TRPA1 | O75762 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | ICMT | O60725 | 4/20 | 0.60 |
| ▸ | FNTA | P49354 | 5/20 | 0.54 |
| ▸ | FNTB | P49356 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Farnesylthioacetic Acid SCHEMBL1962463 | 1.00 | MAPT (1.00) | MAPTKMT2ATRPA1MEN1ALDH1A1 | |
| SCHEMBL14660861 | 0.98 | MAPT (0.97) | MAPTKMT2ATRPA1MEN1ALDH1A1 | |
| SCHEMBL12793914 | 0.88 | MAPT (0.79) | MAPTKMT2ATRPA1MEN1ALDH1A1 | |
| SCHEMBL3409241 | 0.88 | MAPT (0.79) | MAPTKMT2ATRPA1MEN1ALDH1A1 | |
| SCHEMBL14672118 | 0.88 | MAPT (0.78) | MAPTKMT2ATRPA1MEN1ALDH1A1 | |
| SCHEMBL14672111 | 0.86 | MAPT (0.76) | MAPTKMT2ATRPA1MEN1ALDH1A1 | |
| SCHEMBL7771964 | 0.85 | MAPT (0.73) | MAPTKMT2ATRPA1MEN1ALDH1A1 | |
| SCHEMBL3710993 | 0.85 | MAPT (0.73) | MAPTKMT2ATRPA1MEN1ALDH1A1 | |
| SCHEMBL4032129 | 0.84 | MAPT (0.72) | MAPTKMT2ATRPA1MEN1ALDH1A1 | |
| SCHEMBL2879944 | 0.83 | ICMT (0.75) | MAPTKMT2ATRPA1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170333483-A1 | METHODS FOR ENHANCING HEMATOPOIETIC STEM/PROGENITOR CELL ENGRAFTMENT | CHILDREN'S MEDICAL CENTER CORPORATION | 2017-11-23 | — | — | US | disclosed |
| US-20170333483-A1 | METHODS FOR ENHANCING HEMATOPOIETIC STEM/PROGENITOR CELL ENGRAFTMENT | CHILDREN'S MEDICAL CENTER CORPORATION | 2017-11-23 | — | — | US | disclosed |
| US-9737567-B2 | Methods for enhancing hematopoietic stem/progenitor cell engraftment | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2017-08-22 | — | — | US | disclosed |
| US-9737567-B2 | Methods for enhancing hematopoietic stem/progenitor cell engraftment | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2017-08-22 | — | — | US | disclosed |
| US-20150272996-A1 | METHODS FOR ENHANCING HEMATOPOIETIC STEM/PROGENITOR CELL ENGRAFTMENT | CHILDREN'S MEDICAL CENTER CORPORATION | 2015-10-01 | — | — | US | disclosed |
| US-20150272996-A1 | METHODS FOR ENHANCING HEMATOPOIETIC STEM/PROGENITOR CELL ENGRAFTMENT | CHILDREN'S MEDICAL CENTER CORPORATION | 2015-10-01 | — | — | US | disclosed |
| US-9051548-B2 | Methods for enhancing hematopoietic stem/progenitor cell engraftment | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2015-06-09 | — | — | US | disclosed |
| US-9051548-B2 | Methods for enhancing hematopoietic stem/progenitor cell engraftment | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2015-06-09 | — | — | US | disclosed |
| WO-2013016531-A2 | COMPOUNDS AND METHODS FOR USE IN TREATING NEOPLASIA AND CANCER | PURDUE RESEARCH FOUNDATION (US) | 2013-01-31 | — | — | WO | disclosed |
| US-6251882-B1 | TREATING LEUKEMIA, BREAST CANCER, PROSTATE CANCER, OR BRAIN TUMOR | PARKER HUGHES INSTITUTE | 2001-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150272996-A1 | METHODS FOR ENHANCING HEMATOPOIETIC STEM/PROGENITOR CELL ENGRAFTMENT | HCLS1, HGF, MCL1 | MAPT 4785/4885KMT2A 1244/4885TRPA1 4378/4885 |
| US-20170333483-A1 | METHODS FOR ENHANCING HEMATOPOIETIC STEM/PROGENITOR CELL ENGRAFTMENT | HCLS1, HGF, MCL1 | MAPT 4785/4885KMT2A 1244/4885TRPA1 4378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.