Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 10/20 | 0.60 |
| ▸ | CA12 | O43570 | 5/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | RPA1 | P27694 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | MARS1 | P56192 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19533624 | 0.88 | ALPL (0.47) | ALPLCA12TP53RPA1KDM4E | |
| SCHEMBL19544616 | 0.81 | ALPL (0.65) | ALPLCA12TP53CA9 | |
| SCHEMBL1414100 | 0.76 | ALPL (1.00) | ALPLCA12TP53RPA1KDM4E | |
| SCHEMBL726574 | 0.75 | TP53 (1.00) | ALPLCA12TP53RPA1CA9 | |
| SCHEMBL23803931 | 0.74 | ALPL (0.73) | ALPLCA12TP53RPA1KDM4E | |
| SCHEMBL3447352 | 0.74 | ALPL (1.00) | ALPLCA12TP53RPA1KDM4E | |
| SCHEMBL15094586 | 0.74 | ALPL (1.00) | ALPLCA12TP53RPA1KDM4E | |
| SCHEMBL645330 | 0.74 | ALPL (1.00) | ALPLCA12TP53RPA1KDM4E | |
| SCHEMBL1415732 | 0.73 | ALPL (1.00) | ALPLCA12TP53RPA1KDM4E | |
| SCHEMBL222852 | 0.72 | TP53 (0.74) | ALPLCA12TP53RPA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |