Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19624845 | 0.91 | MAPT (0.54) | MAPTALDH1A1MAPK10AURKARIPK1 | |
| SCHEMBL19544607 | 0.89 | MAPK10 (0.43) | MAPTALDH1A1MAPK10AURKARIPK1 | |
| SCHEMBL25060301 | 0.80 | MAPT (0.44) | MAPTALDH1A1MAPK10AURKARIPK1 | |
| SCHEMBL19544883 | 0.80 | MAPT (0.44) | MAPTALDH1A1MAPK10AURKARIPK1 | |
| SCHEMBL19544978 | 0.78 | MAPT (0.67) | MAPTALDH1A1RAB9ANPC1L3MBTL1 | |
| SCHEMBL5317300 | 0.77 | HDAC6 (0.54) | MAPTALDH1A1MAPK10AURKARIPK1 | |
| SCHEMBL27321802 | 0.77 | RAB9A (0.63) | MAPTALDH1A1MAPK10AURKARIPK1 | |
| SCHEMBL19533582 | 0.76 | HRH3 (0.35) | MAPTALDH1A1KDM4EHSD17B10ALPL | |
| SCHEMBL19624694 | 0.75 | MAPT (0.46) | MAPTALDH1A1MAPK10AURKARIPK1 | |
| SCHEMBL19544627 | 0.74 | MAPK10 (0.44) | MAPTALDH1A1MAPK10AURKARIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-B1 | BTK INHIBITOR | HUBEI BIO PHARMACEUTICAL INDUSTRIAL TECH INSTITUTE INC (CN) | 2023-02-22 | — | — | EP | disclosed |
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |