Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19624845 | 0.88 | MAPT (0.54) | MAPTALDH1A1MAPK10AURKARIPK1 | |
| SCHEMBL19544883 | 0.86 | MAPT (0.44) | MAPTALDH1A1MAPK10AURKARIPK1 | |
| SCHEMBL19624848 | 0.80 | MAPT (0.50) | MAPTALDH1A1MAPK10AURKARIPK1 | |
| SCHEMBL19544607 | 0.78 | MAPK10 (0.43) | MAPTALDH1A1MAPK10AURKARIPK1 | |
| SCHEMBL25060299 | 0.77 | KDM4E (0.46) | MAPTALDH1A1MAPK10AURKARIPK1 | |
| SCHEMBL19544627 | 0.76 | MAPK10 (0.44) | MAPTALDH1A1MAPK10AURKARIPK1 | |
| SCHEMBL19544602 | 0.74 | MAPT (0.73) | MAPTALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL19533576 | 0.73 | HRH3 (0.42) | MAPTALDH1A1HRH3 | |
| SCHEMBL17966240 | 0.72 | SMN1; SMN2 (0.60) | MAPTALDH1A1MAPK10KDM4ENPC1 | |
| SCHEMBL648130 | 0.71 | HPGDS (0.55) | MAPTALDH1A1MAPK10AURKARIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-B1 | BTK INHIBITOR | HUBEI BIO PHARMACEUTICAL INDUSTRIAL TECH INSTITUTE INC (CN) | 2023-02-22 | — | — | EP | disclosed |