Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 18/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19624892 | 0.94 | BTK (0.52) | BTKEGFRLCK | |
| SCHEMBL25060477 | 0.88 | BTK (0.48) | BTKEGFRLCK | |
| SCHEMBL19624641 | 0.83 | BTK (0.52) | BTKEGFRLCK | |
| SCHEMBL25060294 | 0.83 | BTK (0.49) | BTKEGFRLCK | |
| SCHEMBL19624825 | 0.82 | USP30 (0.47) | BTKEGFRLCKTNK2 | |
| SCHEMBL16597892 | 0.81 | BTK (0.55) | BTKEGFRLCKTNK2 | |
| SCHEMBL16597822 | 0.81 | BTK (0.55) | BTKEGFRLCKTNK2 | |
| SCHEMBL16597760 | 0.81 | BTK (0.55) | BTKEGFRLCKTNK2 | |
| SCHEMBL19149030 | 0.80 | BTK (0.74) | BTKEGFRLCK | |
| SCHEMBL19149031 | 0.80 | BTK (0.74) | BTKEGFRLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-B1 | BTK INHIBITOR | HUBEI BIO PHARMACEUTICAL INDUSTRIAL TECH INSTITUTE INC (CN) | 2023-02-22 | — | — | EP | disclosed |
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |