Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2888170 | 0.78 | MAPT (0.63) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL19533574 | 0.76 | ALPL (0.53) | NPC1RAB9AMAPTALPLCA9 | |
| SCHEMBL14814661 | 0.73 | CA12 (0.56) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL28092499 | 0.73 | ALPL (0.56) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL18695560 | 0.73 | HCAR2 (0.39) | HRH3KCNH2 | |
| SCHEMBL19544602 | 0.72 | MAPT (0.73) | KMT2ANPC1RAB9AMAPTALPL | |
| SCHEMBL1869857 | 0.72 | POLB (0.57) | RAB9AMAPTBTKLMNAL3MBTL1 | |
| SCHEMBL15382502 | 0.71 | ALDH1A1 (0.53) | HRH3KCNH2MAP4K4LMNASMN1; SMN2 | |
| SCHEMBL21051917 | 0.71 | MKNK1 (0.45) | RAB9AMAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL19624967 | 0.70 | ALDH1A1 (0.40) | HRH3NPC1RAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |