SCHEMBL19625539

SCHEMBL19625539

Cc1cccc(C(C)C)c1/N=C1C(=N/c2c(C)cccc2C(C)C)/c2cccc3cccc/1c23

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.38
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 5/20 0.35
TSHR P16473 3/20 0.35
HSD17B10 Q99714 3/20 0.35
MAPK1 P28482 2/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KCNN2 Q9H2S1 5/20 0.33
KCNN3 Q9UGI6 5/20 0.33
LMNA P02545 3/20 0.33
HPGD P15428 3/20 0.33
CYP3A4 P08684 2/20 0.33
CASP1 P29466 2/20 0.33
CASP7 P55210 2/20 0.33
HIF1A Q16665 2/20 0.33
PABPC1 P11940 1/20 0.33
DNMT1 P26358 1/20 0.33
FAAH O00519 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19625542 0.98 POLB (0.37) POLBMEN1KMT2AALDH1A1TSHR
SCHEMBL5589772 0.95 POLB (0.40) POLBMEN1KMT2AALDH1A1TSHR
SCHEMBL5589365 0.94 POLB (0.39) POLBMEN1KMT2AALDH1A1TSHR
SCHEMBL5138932 0.90 ALDH1A1 (0.40) MEN1KMT2AALDH1A1TSHRHSD17B10
SCHEMBL12923294 0.90 ALDH1A1 (0.40) MEN1KMT2AALDH1A1TSHRHSD17B10
SCHEMBL987736 0.90 ALDH1A1 (0.40) MEN1KMT2AALDH1A1TSHRHSD17B10
SCHEMBL987735 0.90 ALDH1A1 (0.40) MEN1KMT2AALDH1A1TSHRHSD17B10
SCHEMBL21727826 0.89 LMNA (0.34) POLBMEN1KMT2AALDH1A1TSHR
SCHEMBL5587463 0.88 ALDH1A1 (0.39) MEN1KMT2AALDH1A1TSHRHSD17B10
Hydrochloric Acid SCHEMBL8670038 0.87 ALDH1A1 (0.38) MEN1KMT2AALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11332552-B2 Low pressure process for preparing low-density polyethylene CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2022-05-17 US disclosed
US-10961331-B2 Ethylene homopolymers with a reverse short chain branch distribution CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2021-03-30 US disclosed
WO-2020131442-A1 ETHYLENE HOMOPOLYMERS WITH A REVERSE SHORT CHAIN BRANCH DISTRIBUTION CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2020-06-25 WO disclosed
US-20200199265-A1 Ethylene Homopolymers with a Reverse Short Chain Branch Distribution CHEVRON PHILLIPS CHEMICAL COMPANY LP 2020-06-25 US disclosed
US-20170335022-A1 LOW PRESSURE PROCESS FOR PREPARING LOW-DENSITY POLYETHYLENE CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2017-11-23 US disclosed
US-20170335022-A1 LOW PRESSURE PROCESS FOR PREPARING LOW-DENSITY POLYETHYLENE CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2017-11-23 US disclosed