SCHEMBL19625541

SCHEMBL19625541

CCc1cccc(C)c1/N=C1C(=N/c2c(C)cccc2CC)/c2cccc3cccc/1c23

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
CYP1B1 Q16678 1/20 0.40
GABRA1 P14867 3/20 0.40
GABRB2 P47870 3/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 6/20 0.37
CES2 O00748 1/20 0.37
BCHE P06276 1/20 0.37
CES1 P23141 1/20 0.37
MCL1 Q07820 1/20 0.37
TYMS P04818 2/20 0.36
HSD17B10 Q99714 2/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KDM4E B2RXH2 3/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19625543 0.90 CYP1B1 (0.44) POLBCYP1B1GABRA1GABRB2MEN1
SCHEMBL5588478 0.84 POLB (0.49) POLBCYP1B1MEN1KMT2AALDH1A1
SCHEMBL21563329 0.84 POLB (0.49) POLBCYP1B1MEN1KMT2AALDH1A1
SCHEMBL5588472 0.84 POLB (0.49) POLBCYP1B1MEN1KMT2AALDH1A1
SCHEMBL31619719 0.84 CYP1B1 (0.40) POLBCYP1B1GABRA1GABRB2MEN1
SCHEMBL5588451 0.83 POLB (0.47) POLBCYP1B1MEN1KMT2AALDH1A1
Bromide SCHEMBL17835968 0.81 POLB (0.46) POLBCYP1B1MEN1KMT2AALDH1A1
SCHEMBL15624720 0.79 POLB (0.42) POLBMEN1KMT2AALDH1A1CES2
SCHEMBL29310670 0.79 GABRA1 (0.41) POLBGABRA1GABRB2PKM
SCHEMBL17835969 0.78 POLB (0.44) POLBCYP1B1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11332552-B2 Low pressure process for preparing low-density polyethylene CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2022-05-17 US disclosed
US-10961331-B2 Ethylene homopolymers with a reverse short chain branch distribution CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2021-03-30 US disclosed
WO-2020131442-A1 ETHYLENE HOMOPOLYMERS WITH A REVERSE SHORT CHAIN BRANCH DISTRIBUTION CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2020-06-25 WO disclosed
US-20200199265-A1 Ethylene Homopolymers with a Reverse Short Chain Branch Distribution CHEVRON PHILLIPS CHEMICAL COMPANY LP 2020-06-25 US disclosed
US-20170335022-A1 LOW PRESSURE PROCESS FOR PREPARING LOW-DENSITY POLYETHYLENE CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2017-11-23 US disclosed
US-20170335022-A1 LOW PRESSURE PROCESS FOR PREPARING LOW-DENSITY POLYETHYLENE CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2017-11-23 US disclosed