Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspirin SCHEMBL4094496 | 0.94 | KDM4E (0.58) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL9643351 | 0.86 | GSR (0.46) | KMT2ATDP1MAPTDPP7DPP8 | |
| Aspirin SCHEMBL29743139 | 0.84 | KDM4E (0.60) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| Aspirin SCHEMBL25877 | 0.84 | KDM4E (0.60) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| Aspirin SCHEMBL25878 | 0.84 | KDM4E (0.60) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| Aspirin SCHEMBL4834297 | 0.84 | KDM4E (0.60) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| Aspirin SCHEMBL11851702 | 0.84 | KDM4E (0.60) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL28311048 | 0.83 | KDM4E (0.41) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL14988934 | 0.82 | KDM4E (0.49) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| Aspirin SCHEMBL19030830 | 0.81 | KDM4E (0.56) | KDM4EKMT2AMEN1RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200039921-A1 | ANTIFIBRINOLYTIC COMPOUNDS | CHIBBER BAKSHY A (US) | 2020-02-06 | — | — | US | disclosed |
| US-10202331-B2 | Antifibrinolytic compounds | THROMBOLYTICS LLC (US) | 2019-02-12 | — | — | US | disclosed |
| US-20170334834-A1 | ANTIFIBRINOLYTIC COMPOUNDS | THROMBOLYTICS, LLC (US) | 2017-11-23 | — | — | US | disclosed |
| US-20170334834-A1 | ANTIFIBRINOLYTIC COMPOUNDS | THROMBOLYTICS, LLC (US) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10202331-B2 | Antifibrinolytic compounds | F2, FGB, SERPINC1 | KDM4E 415/4885KMT2A 823/4885MEN1 3622/4885 |
| US-20170334834-A1 | ANTIFIBRINOLYTIC COMPOUNDS | F2, SERPINC1, F12 | KDM4E 1344/4885KMT2A 2762/4885MEN1 3440/4885 |
| US-20200039921-A1 | ANTIFIBRINOLYTIC COMPOUNDS | F2, SERPINC1, F12 | KDM4E 1344/4885KMT2A 2762/4885MEN1 3440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.