Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 2/20 | 0.61 |
| ▸ | CDC25B | P30305 | 2/20 | 0.61 |
| ▸ | CDC25C | P30307 | 2/20 | 0.61 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.61 |
| ▸ | ATP4A | P20648 | 2/20 | 0.52 |
| ▸ | ATP4B | P51164 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19626484 | 0.85 | TSHR (0.57) | CDC25ACDC25BCDC25CDUSP3HTT | |
| SCHEMBL19625424 | 0.85 | CDC25A (0.57) | CDC25ACDC25BCDC25CDUSP3MAPT | |
| SCHEMBL12647916 | 0.78 | NPC1 (0.67) | CDC25ACDC25BCDC25CDUSP3HTT | |
| SCHEMBL19626500 | 0.78 | MAPT (0.54) | CDC25ACDC25BCDC25CDUSP3ATP4A | |
| SCHEMBL19627006 | 0.77 | MAPT (0.53) | CDC25ACDC25BCDC25CDUSP3ATP4A | |
| SCHEMBL19626562 | 0.77 | HTT (0.56) | CDC25ACDC25BCDC25CDUSP3ATP4A | |
| SCHEMBL19626563 | 0.77 | HTT (0.59) | CDC25ACDC25BCDC25CDUSP3ATP4A | |
| SCHEMBL19626604 | 0.77 | HTT (0.53) | CDC25ACDC25BCDC25CDUSP3ATP4A | |
| SCHEMBL17626276 | 0.77 | CDC25A (0.51) | CDC25ACDC25BCDC25CDUSP3MAPT | |
| SCHEMBL19627017 | 0.74 | MAPT (0.50) | CDC25ACDC25BCDC25CDUSP3ATP4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334912-A1 | Purine Diones As Wnt Pathway Modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334912-A1 | Purine Diones As Wnt Pathway Modulators | WNT1, WNT3A, CTNNB1 | CDC25A 3229/4885CDC25B 3454/4885CDC25C 3034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.