SCHEMBL196276

SCHEMBL196276

COCCCCCCCCC=O

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
FAAH O00519 2/20 0.46
TRPV1 Q8NER1 2/20 0.46
HIF1A Q16665 1/20 0.45
ALDH1A1 P00352 2/20 0.44
LPAR2 Q9HBW0 4/20 0.35
LPAR3 Q9UBY5 4/20 0.35
LPAR1 Q92633 2/20 0.35
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7926944 1.00 TSHR (0.52) TSHRFAAHTRPV1HIF1AALDH1A1
SCHEMBL17923466 1.00 TSHR (0.52) TSHRFAAHTRPV1HIF1AALDH1A1
SCHEMBL9431529 1.00 TSHR (0.52) TSHRFAAHTRPV1HIF1AALDH1A1
SCHEMBL19287109 1.00 TSHR (0.52) TSHRFAAHTRPV1HIF1AALDH1A1
SCHEMBL11575727 1.00 TSHR (0.52) TSHRFAAHTRPV1HIF1AALDH1A1
SCHEMBL179941 1.00 TSHR (0.52) TSHRFAAHTRPV1HIF1AALDH1A1
SCHEMBL2094913 1.00
SCHEMBL11251398 1.00 TSHR (0.52) TSHRFAAHTRPV1HIF1AALDH1A1
SCHEMBL994389 0.97
SCHEMBL481638 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115806503-B Selective histone deacetylase inhibitor and preparation method and application thereof 中国海洋大学 2025-03-07 CN disclosed
US-9943532-B2 Iminosugars and methods of treating viral diseases EMERGENT VIROLOGY LLC (US) 2018-04-17 US disclosed
US-20170304333-A1 IMINOSUGARS AND METHODS OF TREATING VIRAL DISEASES EMERGENT VIROLOGY LLC (US) 2017-10-26 US disclosed
EP-2320886-B1 GLUCOSYLCERAMIDE SYNTHASE INHIBITION FOR THE TREATMENT OF COLLAPSING GLOMERULOPATHY AND OTHER GLOMERULAR DISEASE GENZYME CORP (US) 2017-06-28 EP disclosed
US-9579334-B2 Iminosugars and methods of treating viral diseases EMERGENT VIROLOGY LLC (US) 2017-02-28 US disclosed
US-20160243096-A1 METHODS OF TREATING ORTHOMYXOVIRAL INFECTIONS EMERGENT VIROLOGY LLC (US) 2016-08-25 US disclosed
US-20160243097-A1 METHODS OF TREATING POXVIRAL INFECTIONS EMERGENT VIROLOGY LLC (US) 2016-08-25 US disclosed
EP-2398321-B1 IMINOSUGARS AND METHODS OF TREATING VIRAL DISEASES UNITED THERAPEUTICS CORP (US) 2015-11-25 EP disclosed
EP-2400843-B1 IMINOSUGARS AND METHODS OF TREATING ARENAVIRAL INFECTIONS UNITED THERAPEUTICS CORP (US) 2015-11-11 EP disclosed
US-20150224128-A1 IMINOSUGARS AND METHODS OF TREATING VIRAL DISEASES UNITED THERAPEUTICS CORPORATION (US) 2015-08-13 US disclosed
US-20110065752-A1 METHODS OF TREATING ORTHOMYXOVIRAL INFECTIONS UNITED THERAPEUTICS CORPORATION 2011-03-17 US disclosed
WO-2011028781-A1 METHODS OF TREATING POXVIRAL INFECTIONS UNITED THERAPEUTICS CORPORATION (US) 2011-03-10 WO disclosed
WO-2011028779-A1 IMINOSUGARS AND METHODS OF TREATING FILOVIRAL DISEASES UNITED THERAPEUTICS CORPORATION (US) 2011-03-10 WO disclosed
WO-2011028775-A1 METHODS OF TREATING ORTHOMYXOVIRAL INFECTIONS UNITED THERAPEUTICS CORPORATION (US) 2011-03-10 WO disclosed
US-20100317696-A1 IMINOSUGARS AND METHODS OF TREATING BUNYAVIRAL AND TOGAVIRAL DISEASES UNITED THERAPEUTICS CORPORATION 2010-12-16 US disclosed
WO-2010144759-A1 IMINOSUGARS AND METHODS OF TREATING BUNYAVIRAL AND TOGAVIRAL DISEASES UNITED THERAPEUTICS CORPORATION (US) 2010-12-16 WO disclosed
WO-2010099064-A1 IMINOSUGARS AND METHODS OF TREATING ARENAVIRAL INFECTIONS UNITED THERAPEUTICS CORPORATION (US) 2010-09-02 WO disclosed
US-20100222383-A1 Iminosugars and methods of treating viral diseases UNITED THERAPEUTICS CORPORATION 2010-09-02 US disclosed
US-20100222384-A1 Iminosugars and methods of treating arenaviral infections UNITED THERAPEUTICS CORPORATION 2010-09-02 US disclosed
WO-2010096764-A1 IMINOSUGARS AND METHODS OF TREATING VIRAL DISEASES UNITED THERAPEUTICS CORPORATION (US) 2010-08-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100222383-A1 Iminosugars and methods of treating viral diseases GBA1, UGCG, HAVCR2 TSHR 3979/4885FAAH 720/4885TRPV1 4350/4885
US-20160243096-A1 METHODS OF TREATING ORTHOMYXOVIRAL INFECTIONS EIF2AK2, ENGASE, MANBA TSHR 4202/4885FAAH 2070/4885TRPV1 4026/4885
US-20100222384-A1 Iminosugars and methods of treating arenaviral infections EIF2AK2, UGCG, ASAH2 TSHR 4598/4885FAAH 1360/4885TRPV1 2475/4885
US-20160243097-A1 METHODS OF TREATING POXVIRAL INFECTIONS DPM1, EIF2AK2, DERA TSHR 4639/4885FAAH 2753/4885TRPV1 3659/4885
US-20150224128-A1 IMINOSUGARS AND METHODS OF TREATING VIRAL DISEASES GBA1, UGCG, HAVCR2 TSHR 3979/4885FAAH 720/4885TRPV1 4350/4885
US-20110065752-A1 METHODS OF TREATING ORTHOMYXOVIRAL INFECTIONS EIF2AK2, ENGASE, MANBA TSHR 4202/4885FAAH 2070/4885TRPV1 4026/4885
US-20100317696-A1 IMINOSUGARS AND METHODS OF TREATING BUNYAVIRAL AND TOGAVIRAL DISEASES EIF2AK2, ENGASE, IPO9 TSHR 4121/4885FAAH 2663/4885TRPV1 4360/4885
US-20170304333-A1 IMINOSUGARS AND METHODS OF TREATING VIRAL DISEASES GBA1, UGCG, HAVCR2 TSHR 3979/4885FAAH 720/4885TRPV1 4350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.