⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20577349 | 0.97 | — | — | |
| SCHEMBL994389 | 0.92 | — | — | |
| SCHEMBL196276 | 0.89 | TSHR (0.52) | — | |
| SCHEMBL11251398 | 0.89 | TSHR (0.52) | — | |
| SCHEMBL11575727 | 0.89 | TSHR (0.52) | — | |
| SCHEMBL179941 | 0.89 | TSHR (0.52) | — | |
| SCHEMBL2094913 | 0.89 | — | — | |
| SCHEMBL19287109 | 0.89 | TSHR (0.52) | — | |
| SCHEMBL17923466 | 0.89 | TSHR (0.52) | — | |
| SCHEMBL7926944 | 0.89 | TSHR (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693507-A | Inhibitor compounds | 奈奥芬莱有限公司 | 2024-03-12 | — | — | CN | claimed |
| CN-117120476-A | Antibodies specific for structurally disordered sequences | XL-普洛坦公司 | 2023-11-24 | — | — | CN | claimed |
| EP-4267628-A1 | ANTIBODIES SPECIFIC FOR STRUCTURALLY DISORDERED SEQUENCES | XL-protein GmbH (DE) | 2023-11-01 | — | — | EP | claimed |
| WO-2022136582-A1 | ANTIBODIES SPECIFIC FOR STRUCTURALLY DISORDERED SEQUENCES | XL-PROTEIN GMBH (DE) | 2022-06-30 | — | — | WO | claimed |
| US-20200282071-A1 | CONJUGATES OF PROTEIN DRUGS AND P/A PEPTIDES | XL-PROTEIN GMBH (DE) | 2020-09-10 | — | — | US | claimed |
| EP-3641827-A1 | CONJUGATES OF PROTEIN DRUGS AND P/A PEPTIDES | XL-protein GmbH (DE) | 2020-04-29 | — | — | EP | claimed |
| CN-110891612-A | Conjugates of protein drugs and P/A peptides | XL-蛋白有限责任公司 | 2020-03-17 | — | — | CN | claimed |
| WO-2018234455-A1 | CONJUGATES OF PROTEIN DRUGS AND P/A PEPTIDES | XL-PROTEIN GMBH (DE) | 2018-12-27 | — | — | WO | claimed |
| EP-1492536-B1 | 4-(N-PHENYLAMINO)-QUINAZOLINES / QUINOLINES AS TYROSINE KINASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA (DE) | 2012-05-09 | — | — | EP | claimed |
| EP-1567567-B1 | LOW POLYDISPERSITY POLY-HEMA COMPOSITIONS | JOHNSON & JOHNSON VISION CARE (US) | 2010-09-08 | — | — | EP | claimed |
| WO-2003077792-A2 | LOW POLYDISPERSITY POLY-HEMA COMPOSITIONS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2003-09-25 | — | — | WO | claimed |
| US-6617324-B1 | Phenyl, cyclohexyl and pyridinyl or pyrimidinyl-substituted | G. D. SEARLE & COMPANY | 2003-09-09 | — | — | US | claimed |
| US-6514977-B1 | For treating p38 kinase mediated disorders | G.D. SEARLE & COMPANY | 2003-02-04 | — | — | US | claimed |
| US-6423713-B1 | Substituted pyrazoles as p38 kinase inhibitors | G. D. SEARLE & COMPANY | 2002-07-23 | — | — | US | claimed |
| CN-1342157-A | Substituted pyrazoles ASP38 kinase inhibitors | SEARLE & CO (US) | 2002-03-27 | — | — | CN | claimed |
| EP-1144403-A1 | SUBSTITUED PYRAZOLES AS P38 KINASE INHIBITORS | G.D. SEARLE & CO. (US) | 2001-10-17 | — | — | EP | claimed |
| WO-2000031063-A1 | SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS | G.D. SEARLE & CO. (US) | 2000-06-02 | — | — | WO | claimed |
| EP-0191542-B1 | ARYLCYCLOBUTYLALKYL AMINES AND THEIR USE AS ANTIDEPRESSIVE MEDICINES | The Boots Company PLC (GB) | 1988-06-08 | — | — | EP | claimed |
| EP-0191542-A1 | Arylcyclobutylalkyl amines and their use as antidepressive medicines | The Boots Company PLC (GB) | 1986-08-20 | — | — | EP | claimed |
| US-4590209-A | INOTROPIC, ANTIARRHYTHMIA, AND ANTILIPEMIC AGENTS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1986-05-20 | — | — | US | claimed |