⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9431529 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL7926944 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL17923466 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL11251398 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL11575727 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL19287109 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL2094913 | 0.97 | — | — | |
| SCHEMBL179941 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL196276 | 0.97 | TSHR (0.52) | — | |
| SCHEMBL481638 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064152-A1 | TRICYCLIC SULFAMIDES AND SULTAMS | MERCK SHARP & DOHME LLC (US) | 2023-04-20 | — | — | WO | claimed |
| US-20250171463-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. | 2025-05-29 | — | — | US | disclosed |
| US-20250066627-A1 | GRANULAR COMPOSITION CONTAINING GRAPHENE AND A PARTICULATE MATERIAL, AND METHOD FOR PRODUCING IT | DIRECTA PLUS S.P.A. (IT) | 2025-02-27 | — | — | US | disclosed |
| US-11993578-B2 | Pyrazole-3-carboxylic acid amide derivative and pest control agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2024-05-28 | — | — | US | disclosed |
| US-11964957-B2 | Pyrazole derivative and harmful organism-controlling agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2024-04-23 | — | — | US | disclosed |
| EP-3808738-B1 | PYRAZOLE DERIVATIVE AND HARMFUL ORGANISM-CONTROLLING AGENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2024-04-17 | — | — | EP | disclosed |
| CN-112236421-B | Pyrazole derivatives and pest control agents | 组合化学工业株式会社 | 2023-12-26 | — | — | CN | disclosed |
| CN-117157081-A | Nucleotide derivative with anti-tumor activity, and pharmaceutical composition and application thereof | 南京赛弗斯医药科技有限公司 | 2023-12-01 | — | — | CN | disclosed |
| EP-4273197-A1 | GRANULAR COMPOSITION CONTAINING GRAPHENE AND A PARTICULATE MATERIAL, AND METHOD FOR PRODUCING IT | Directa Plus S.p.A. (IT) | 2023-11-08 | — | — | EP | disclosed |
| CN-113260604-B | Actinic-ray-or radiation-sensitive resin composition, resist film, pattern forming method, and method for manufacturing electronic device | 富士胶片株式会社 | 2023-10-17 | — | — | CN | disclosed |
| EP-1603885-A1 | FUSED TRI AND TETRA-CYCLIC PYRAZOLE KINASE INHIBITORS | Abbott Laboratories (US) | 2005-12-14 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| EP-1124810-B1 | 2-AMINO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA SPA (IT) | 2005-05-04 | — | — | EP | disclosed |
| US-20040259904-A1 | Fused tri and tetra-cyclic pyrazole kinase inhibitors | ABBVIE INC. | 2004-12-23 | — | — | US | disclosed |
| WO-2004080973-A1 | FUSED TRI AND TETRA-CYCLIC PYRAZOLE KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2004-09-23 | — | — | WO | disclosed |
| EP-1124810-A1 | 2-AMINO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026202-A1 | 2-AMINO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2000-05-11 | — | — | WO | disclosed |
| US-5215995-A | For treatment of baldness or alopecia | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| EP-0528304-A2 | Binder compositions and their use | BAYER AG (DE) | 1993-02-24 | — | — | EP | disclosed |
| EP-0423714-A2 | Hair revitalizing agent | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-24 | — | — | EP | disclosed |