SCHEMBL19628024

SCHEMBL19628024

Cc1c(CN2CCCC2)cccc1CN1CCN(C(=O)OC(C)C(F)(F)F)CC1

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 18/20 0.57
ABHD6 Q9BV23 10/20 0.57
PLA2G7 Q13093 8/20 0.57
CYP2D6 P10635 1/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19627999 0.92 MGLL (0.52) MGLLABHD6PLA2G7KDM4EALDH1A1
SCHEMBL19627996 0.90 MGLL (0.58) MGLLABHD6PLA2G7KDM4EALDH1A1
SCHEMBL19628003 0.90 MGLL (0.51) MGLLABHD6PLA2G7KDM4EALDH1A1
SCHEMBL19627997 0.90 MGLL (0.51) MGLLABHD6PLA2G7KDM4EALDH1A1
SCHEMBL18064859 0.90 MGLL (0.71) MGLLABHD6PLA2G7CYP2D6
SCHEMBL19628005 0.88 NPSR1 (0.50) MGLLABHD6PLA2G7KDM4EALDH1A1
SCHEMBL19628011 0.88 MGLL (0.48) MGLLABHD6PLA2G7CYP2D6
SCHEMBL19628015 0.88 MGLL (0.48) MGLLABHD6PLA2G7CYP2D6
SCHEMBL19628033 0.83 MGLL (0.51) MGLLABHD6PLA2G7CYP2D6
SCHEMBL19628004 0.83 MGLL (0.45) MGLLABHD6PLA2G7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170334874-A1 PIPERAZINE CARBAMATES AND METHODS OF MAKING AND USING SAME H. LUNDBECK A/S (DK) 2017-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170334874-A1 PIPERAZINE CARBAMATES AND METHODS OF MAKING AND USING SAME ABHD6, RABL6, ABHD16A MGLL 46/4885ABHD6 1/4885PLA2G7 204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.