Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | ACR | P10323 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14515831 | 0.85 | KMT2A (0.55) | KMT2ALMNAMAPTHPGDALDH1A1 | |
| SCHEMBL10040438 | 0.82 | PRSS1 (0.58) | KMT2ALMNAMAPTHPGDALDH1A1 | |
| SCHEMBL23720647 | 0.80 | KMT2A (0.50) | KMT2ALMNAMAPTHPGDALDH1A1 | |
| SCHEMBL20693207 | 0.78 | HTT (0.59) | KMT2ALMNAMAPTCYP1A2CYP2C9 | |
| SCHEMBL20693210 | 0.78 | THRB (0.44) | KMT2ALMNAMAPTHPGDALDH1A1 | |
| SCHEMBL20693281 | 0.77 | THRB (0.43) | KMT2ALMNAMAPTHPGDALDH1A1 | |
| SCHEMBL21883825 | 0.77 | HTT (0.44) | KMT2ALMNAMAPTHPGDALDH1A1 | |
| SCHEMBL20693138 | 0.77 | HTT (0.44) | KMT2ALMNAMAPTHPGDALDH1A1 | |
| SCHEMBL14204848 | 0.75 | PRSS1 (0.51) | KMT2ALMNAMAPTHPGDALDH1A1 | |
| SCHEMBL12228227 | 0.74 | MAOB (0.47) | KMT2AMAPTHPGDALDH1A1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198586-A1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2017-11-23 | — | — | WO | disclosed |