SCHEMBL19628862

SCHEMBL19628862

Cc1cc(/N=N/c2ccc3c(S(=O)(=O)O)cc(/N=N/c4ccc([N+](=O)[O-])cc4)c(O)c3c2N)ccc1/N=N/c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.60
HPGD P15428 4/20 0.53
MEN1 O00255 3/20 0.53
ALDH1A1 P00352 3/20 0.53
MAPT P10636 3/20 0.53
THRB P10828 3/20 0.53
RECQL P46063 3/20 0.53
BLM P54132 3/20 0.53
KMT2A Q03164 3/20 0.53
CYP3A4 P08684 3/20 0.53
ALOX15 P16050 3/20 0.53
HSD17B10 Q99714 3/20 0.53
APP P05067 2/20 0.53
SNCA P37840 2/20 0.53
CYP2D6 P10635 2/20 0.53
CYP2C9 P11712 2/20 0.53
TSHR P16473 2/20 0.53
CYP2C19 P33261 2/20 0.53
KDM4E B2RXH2 2/20 0.53
TP53 P04637 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19628863 0.90 CYP1A2 (0.48) CYP1A2HPGDMEN1ALDH1A1MAPT
SCHEMBL19628861 0.84 HPGD (0.49) CYP1A2HPGDMEN1ALDH1A1MAPT
SCHEMBL29595328 0.82 CYP1A2 (0.59) CYP1A2HPGDMEN1ALDH1A1MAPT
SCHEMBL15281272 0.81 SENP2 (0.55) CYP1A2HPGDMEN1ALDH1A1MAPT
SCHEMBL17791868 0.80 CYP1A2 (0.77) CYP1A2HPGDMEN1ALDH1A1MAPT
SCHEMBL17778256 0.79 ENPP2 (0.48) CYP1A2HPGDMEN1ALDH1A1MAPT
SCHEMBL2602447 0.79 CYP1A2 (0.53) CYP1A2HPGDMEN1ALDH1A1MAPT
SCHEMBL19628867 0.79 ENPP2 (0.45) CYP1A2HPGDMEN1ALDH1A1MAPT
SCHEMBL16557876 0.78 HPGD (0.54) CYP1A2HPGDMEN1ALDH1A1MAPT
SCHEMBL17778347 0.78 ENPP2 (0.46) CYP1A2HPGDMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170335110-A1 Black Trisazo Dyes, Their Preparation And Their Use LANXESS DEUTSCHLAND GMBH (DE) 2017-11-23 US disclosed