Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19629851 | 0.80 | PGR (0.39) | PGRMEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL29728155 | 0.78 | PGR (0.40) | PGRMEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL19617204 | 0.78 | PGR (0.40) | PGRMEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL4805389 | 0.76 | SLC6A2 (0.47) | PGRMEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL16324464 | 0.75 | PGR (0.34) | PGRMEN1KMT2APDE4APDE4B | |
| SCHEMBL18850723 | 0.75 | PGR (0.39) | PGRMEN1KMT2ASLC6A2PDE4A | |
| SCHEMBL15578891 | 0.75 | PGR (0.39) | PGRMEN1KMT2ASLC6A2PDE4A | |
| SCHEMBL15578711 | 0.73 | PGR (0.39) | PGRMEN1KMT2A | |
| SCHEMBL4804347 | 0.73 | PGR (0.50) | PGRMEN1KMT2APDE4APDE4B | |
| SCHEMBL836635 | 0.72 | PGR (0.36) | PGRMEN1KMT2ASLC6A2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458452-B1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANTI-BACTERIAL AGENTS AND METHOD FOR PRODUCTION | BUGWORKS RES INC (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2017199265-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANTI-BACTERIAL AGENTS AND METHOD FOR PRODUCTION | BUGWORKS RESEARCH INDIA PVT LTD (IN) | 2017-11-23 | — | — | WO | disclosed |