Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619718 | 0.79 | NR3C2 (0.44) | MAPTNR3C2KMT2AMGLLMMP12 | |
| SCHEMBL7270318 | 0.76 | GAA (0.59) | MAPTUSP2POLBBLMPARP1 | |
| SCHEMBL20074155 | 0.74 | ALDH1A1 (0.49) | MAPTUSP2POLBBLMKMT2A | |
| SCHEMBL15845256 | 0.74 | NR3C2 (0.47) | NR3C2NR3C1 | |
| SCHEMBL15595107 | 0.74 | NR3C2 (0.47) | NR3C2NR3C1 | |
| SCHEMBL5260878 | 0.73 | KCNH2 (0.43) | NR3C2 | |
| SCHEMBL24464595 | 0.72 | BRD4 (0.46) | POLBADORA2BKMT2ATDP1SLC6A2 | |
| SCHEMBL8230242 | 0.71 | NR3C2 (0.41) | MAPTUSP2POLBBLMNR3C2 | |
| SCHEMBL4289036 | 0.71 | NR3C2 (0.41) | MAPTUSP2POLBBLMNR3C2 | |
| SCHEMBL4289038 | 0.71 | NR3C2 (0.41) | MAPTUSP2POLBBLMNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017199265-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANTI-BACTERIAL AGENTS AND METHOD FOR PRODUCTION | BUGWORKS RESEARCH INDIA PVT LTD (IN) | 2017-11-23 | — | — | WO | disclosed |