Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | PDE4A | P27815 | 1/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.62 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.60 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.56 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.56 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10528660 | 1.00 | HTT (0.66) | HTTLMNAKMT2APDE4APDE4B | |
| SCHEMBL10527008 | 0.92 | HTT (0.80) | HTTLMNAKMT2AALDH1A1TAS1R3 | |
| Hydrochloric Acid SCHEMBL10528633 | 0.91 | HTT (0.78) | HTTLMNAKMT2AALDH1A1TAS1R3 | |
| SCHEMBL3460628 | 0.88 | HTT (0.83) | HTTLMNAKMT2APDE4APDE4B | |
| SCHEMBL2465110 | 0.88 | HTT (0.83) | HTTLMNAKMT2APDE4APDE4B | |
| SCHEMBL29742388 | 0.88 | HTT (0.83) | HTTLMNAKMT2APDE4APDE4B | |
| SCHEMBL3459886 | 0.88 | HTT (0.83) | HTTLMNAKMT2APDE4APDE4B | |
| SCHEMBL6570868 | 0.87 | LMNA (0.69) | HTTLMNAKMT2APDE4APDE4B | |
| SCHEMBL8160654 | 0.86 | HTT (0.70) | HTTLMNAKMT2APDE4APDE4B | |
| SCHEMBL2468527 | 0.86 | KMT2A (0.67) | HTTLMNAKMT2APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017199103-A1 | BENZAMIDE COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2017-11-23 | — | — | WO | disclosed |