Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.53 |
| ▸ | CPB1 | P15086 | 1/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29790888 | 0.89 | CPB1 (0.61) | CTSLSIRT2SIRT1SIRT3CPB1 | |
| SCHEMBL20827884 | 0.86 | CTSL (0.59) | CTSL | |
| SCHEMBL5929274 | 0.85 | CTSL (0.73) | CTSLSIRT2 | |
| SCHEMBL31045787 | 0.85 | SIRT2 (0.62) | CTSLSIRT2SIRT1SIRT3CPB1 | |
| SCHEMBL20827885 | 0.84 | CAPN1 (0.66) | CTSL | |
| SCHEMBL20827908 | 0.84 | CAPN1 (0.66) | CTSL | |
| SCHEMBL11411256 | 0.84 | CTSL (0.56) | CTSLSIRT2SIRT1SIRT3CPB1 | |
| SCHEMBL27892488 | 0.82 | SIRT2 (0.57) | CTSLSIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL14509093 | 0.82 | CTSL (0.68) | CTSLSIRT2 | |
| SCHEMBL11173853 | 0.82 | CPB1 (0.60) | SIRT2SIRT1SIRT3CPB1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201322-A1 | TREATMENT OF OSTEOARTHRITIS WITH GINGIPAIN BLOCKING AGENTS | Cortexyme, Inc. (US) | 2017-11-23 | — | — | WO | disclosed |