Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.55 |
| ▸ | CDK7 | P50613 | 2/20 | 0.55 |
| ▸ | CDK9 | P50750 | 2/20 | 0.55 |
| ▸ | CCNK | O75909 | 1/20 | 0.55 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.55 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.55 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.55 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.55 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.55 |
| ▸ | CCNH | P51946 | 1/20 | 0.55 |
| ▸ | PIK3C3 | Q8NEB9 | 5/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.51 |
| ▸ | CDK4 | P11802 | 12/20 | 0.50 |
| ▸ | GSK3B | P49841 | 7/20 | 0.50 |
| ▸ | CDK2 | P24941 | 4/20 | 0.50 |
| ▸ | CDK1 | P06493 | 3/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20421895 | 0.92 | CSNK1A1 (0.55) | CSNK1A1CDK7CDK9CCNKCDK13 | |
| SCHEMBL19629618 | 0.92 | CSNK1A1 (0.55) | CSNK1A1CDK7CDK9CCNKCDK13 | |
| SCHEMBL19629619 | 0.92 | CSNK1A1 (0.55) | CSNK1A1CDK7CDK9CCNKCDK13 | |
| SCHEMBL18480591 | 0.92 | CSNK1A1 (0.55) | CSNK1A1CDK7CDK9CCNKCDK13 | |
| SCHEMBL20421794 | 0.91 | CSNK1A1 (0.67) | CSNK1A1CDK7CDK9CCNKCDK13 | |
| SCHEMBL19629622 | 0.91 | CSNK1A1 (0.67) | CSNK1A1CDK7CDK9CCNKCDK13 | |
| SCHEMBL19629620 | 0.91 | CSNK1A1 (0.67) | CSNK1A1CDK7CDK9CCNKCDK13 | |
| SCHEMBL18480113 | 0.90 | PIK3C3 (0.61) | CSNK1A1CDK7CDK9CCNKCDK13 | |
| SCHEMBL25025606 | 0.89 | PIK3C3 (0.55) | CSNK1A1CDK7CDK9CCNKCDK13 | |
| SCHEMBL20421786 | 0.89 | CSNK1A1 (0.52) | CSNK1A1CDK7CDK9CCNKCDK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201069-A1 | OXOINDOLINE DERIVATIVES AS PROTEIN FUNCTION MODULATORS | BIOTHERYX, INC. (US) | 2017-11-23 | — | — | WO | disclosed |