Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.67 |
| ▸ | CDK7 | P50613 | 3/20 | 0.67 |
| ▸ | CDK9 | P50750 | 2/20 | 0.67 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.67 |
| ▸ | CCNK | O75909 | 1/20 | 0.67 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.67 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.67 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.67 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.67 |
| ▸ | CCNH | P51946 | 1/20 | 0.67 |
| ▸ | PIK3C3 | Q8NEB9 | 5/20 | 0.63 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 10/20 | 0.49 |
| ▸ | GSK3B | P49841 | 8/20 | 0.49 |
| ▸ | CDK2 | P24941 | 3/20 | 0.49 |
| ▸ | CDK1 | P06493 | 4/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20421794 | 1.00 | CSNK1A1 (0.67) | CSNK1A1CDK7CDK9CSNK1DCCNK | |
| SCHEMBL19629620 | 1.00 | CSNK1A1 (0.67) | CSNK1A1CDK7CDK9CSNK1DCCNK | |
| SCHEMBL20421802 | 0.96 | CSNK1A1 (0.62) | CSNK1A1CDK7CDK9CSNK1DCCNK | |
| SCHEMBL20421808 | 0.96 | CSNK1A1 (0.62) | CSNK1A1CDK7CDK9CSNK1DCCNK | |
| SCHEMBL20445215 | 0.96 | CSNK1A1 (0.62) | CSNK1A1CDK7CDK9CSNK1DCCNK | |
| SCHEMBL18480120 | 0.96 | CSNK1A1 (0.62) | CSNK1A1CDK7CDK9CSNK1DCCNK | |
| SCHEMBL31307740 | 0.95 | CSNK1A1 (0.61) | CSNK1A1CDK7CDK9CSNK1DCCNK | |
| SCHEMBL19629618 | 0.91 | CSNK1A1 (0.55) | CSNK1A1CDK7CDK9CSNK1DCCNK | |
| SCHEMBL19630864 | 0.91 | CSNK1A1 (0.55) | CSNK1A1CDK7CDK9CSNK1DCCNK | |
| SCHEMBL18480591 | 0.91 | CSNK1A1 (0.55) | CSNK1A1CDK7CDK9CSNK1DCCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207268-A1 | PYRAZOLYLPYRIMIDINES FOR TREATING MALIGNANT SOLID TUMOR | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2024-06-27 | — | — | US | disclosed |
| US-11752151-B2 | Method for enhancing hair growth | BUDDHIST TZU CHI MEDICAL FOUNDATION (TW) | 2023-09-12 | — | — | US | disclosed |
| US-20230053307-A1 | METHOD FOR PREVENTING OR TREATING SKIN DISORDERS AND CONDITIONS | BUDDHIST TZU CHI MEDICAL FOUNDATION (TW) | 2023-02-16 | — | — | US | disclosed |
| US-20230047732-A1 | PYRAZOLYLPYRIMIDINES AND USE THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2023-02-16 | — | — | US | disclosed |
| US-20230024910-A1 | METHOD FOR ENHANCING HAIR GROWTH | BUDDHIST TZU CHI MEDICAL FOUNDATION (TW) | 2023-01-26 | — | — | US | disclosed |
| US-11345714-B2 | Compounds targeting proteins, compositions, methods, and uses thereof | BIOTHERYX, INC. (US) | 2022-05-31 | — | — | US | disclosed |
| EP-3331877-B1 | PYRAZOLE PYRIMIDINE DERIVATIVE AND USES THEREOF | YISSUM RES DEV CO OF HEBREW UNIV JERUSALEM LTD (IL) | 2021-09-22 | — | — | EP | disclosed |
| US-20210251992-A1 | PYRAZOLE PYRIMIDINE DERIVATIVE AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2021-08-19 | — | — | US | disclosed |
| WO-2021146220-A1 | PYRAZOLYLPYRIMIDINES AND USE THEREOF | BIOTHERYX, INC. (US) | 2021-07-22 | — | — | WO | disclosed |
| US-20210139500-A1 | COMPOUNDS TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF | BIOTHERYX, INC. (US) | 2021-05-13 | — | — | US | disclosed |
| US-10376511-B2 | Pyrazole pyrimidine derivative and uses thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2019-08-13 | — | — | US | disclosed |
| US-10336771-B2 | Compounds targeting proteins, compositions, methods, and uses thereof | BIOTHERYX, INC. (US) | 2019-07-02 | — | — | US | disclosed |
| US-10040804-B2 | Compounds targeting proteins, compositions, methods, and uses thereof | BIOTHERYX, INC. (US) | 2018-08-07 | — | — | US | disclosed |
| US-20180214447-A1 | PYRAZOLE PYRIMIDINE DERIVATIVE AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. ISRAELI COMPANY, OF (IL) | 2018-08-02 | — | — | US | disclosed |
| WO-2018118947-A1 | THIENOPYRROLE DERIVATIVES FOR USE IN TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF | BIOTHERYX, INC. (US) | 2018-06-28 | — | — | WO | disclosed |
| US-20180170948-A1 | COMPOUNDS TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF | Bio TheryX, Inc. | 2018-06-21 | — | — | US | disclosed |
| US-9938302-B2 | Chimeric compounds targeting proteins, compositions, methods, and uses thereof | BIOTHERYX, INC. (US) | 2018-04-10 | — | — | US | disclosed |
| US-20170333443-A1 | CHIMERIC COMPOUNDS TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF | BIOTHERYX, INC. | 2017-11-23 | — | — | US | disclosed |
| US-20170334932-A1 | CHIMERIC COMPOUNDS TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF | BIOTHERYX, INC. | 2017-11-23 | — | — | US | disclosed |
| WO-2017201069-A1 | OXOINDOLINE DERIVATIVES AS PROTEIN FUNCTION MODULATORS | BIOTHERYX, INC. (US) | 2017-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230053307-A1 | METHOD FOR PREVENTING OR TREATING SKIN DISORDERS AND CONDITIONS | PACSIN2, CSNK1A1, CSNK2A3 | CSNK1A1 2/4885CDK7 772/4885CDK9 589/4885 |
| US-11345714-B2 | Compounds targeting proteins, compositions, methods, and uses thereof | CKS1B, IKZF3, EPAS1 | CSNK1A1 19/4885CDK7 377/4885CDK9 1056/4885 |
| US-20210139500-A1 | COMPOUNDS TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF | CKS1B, IKZF3, CKS2 | CSNK1A1 20/4885CDK7 272/4885CDK9 954/4885 |
| US-20210251992-A1 | PYRAZOLE PYRIMIDINE DERIVATIVE AND USES THEREOF | IRAK1, IRAK2, IRAK3 | CSNK1A1 5/4885CDK7 238/4885CDK9 137/4885 |
| US-20240207268-A1 | PYRAZOLYLPYRIMIDINES FOR TREATING MALIGNANT SOLID TUMOR | VHL, TP53, TYMP | CSNK1A1 1246/4885CDK7 451/4885CDK9 472/4885 |
| US-20180170948-A1 | COMPOUNDS TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF | CKS1B, IKZF3, EPAS1 | CSNK1A1 19/4885CDK7 377/4885CDK9 1056/4885 |
| US-10376511-B2 | Pyrazole pyrimidine derivative and uses thereof | IRAK1, IRAK2, IRAK3 | CSNK1A1 5/4885CDK7 238/4885CDK9 137/4885 |
| US-10336771-B2 | Compounds targeting proteins, compositions, methods, and uses thereof | CKS1B, IKZF3, EPAS1 | CSNK1A1 19/4885CDK7 377/4885CDK9 1056/4885 |
| US-11752151-B2 | Method for enhancing hair growth | CSNK1A1, CSNK1G1, CSNK2A1 | CSNK1A1 1/4885CDK7 184/4885CDK9 221/4885 |
| US-20230024910-A1 | METHOD FOR ENHANCING HAIR GROWTH | CSNK1A1, CSNK1G1, CSNK2A1 | CSNK1A1 1/4885CDK7 184/4885CDK9 221/4885 |
| US-10040804-B2 | Compounds targeting proteins, compositions, methods, and uses thereof | CKS1B, IKZF3, EPAS1 | CSNK1A1 19/4885CDK7 377/4885CDK9 1056/4885 |
| US-20170333443-A1 | CHIMERIC COMPOUNDS TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF | IKZF3, IKZF1, CKS1B | CSNK1A1 9/4885CDK7 264/4885CDK9 945/4885 |
| US-20180214447-A1 | PYRAZOLE PYRIMIDINE DERIVATIVE AND USES THEREOF | IRAK1, IRAK2, IRAK3 | CSNK1A1 5/4885CDK7 238/4885CDK9 137/4885 |
| US-20170334932-A1 | CHIMERIC COMPOUNDS TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF | IKZF3, IKZF1, CKS1B | CSNK1A1 9/4885CDK7 264/4885CDK9 945/4885 |
| US-20230047732-A1 | PYRAZOLYLPYRIMIDINES AND USE THEREOF | MCL1, THPO, FLT3 | CSNK1A1 4254/4885CDK7 427/4885CDK9 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.