Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19612116 | 0.90 | MEN1 (0.51) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL19631014 | 0.86 | ALDH1A1 (0.44) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| Monoethanolamine SCHEMBL28921820 | 0.84 | MEN1 (0.46) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL19627237 | 0.81 | KDM4E (0.46) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL17770319 | 0.79 | TMPRSS4 (0.55) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL19631018 | 0.79 | DYRK1A (0.63) | MEN1KMT2ANPC1RAB9ADYRK1A | |
| SCHEMBL31237407 | 0.79 | TMPRSS4 (0.55) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL19627232 | 0.77 | KMT2A (0.62) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL19612096 | 0.76 | NPC1 (0.45) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL19612105 | 0.75 | CTSD (0.47) | KMT2ANPC1RAB9ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201313-A1 | NOVEL MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | JIN SHENGKAN (US) | 2017-11-23 | — | — | WO | disclosed |