SCHEMBL4245808

SCHEMBL4245808

CCCCCCn1ccc(N)nc1=O

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 4/20 0.48
TLR8 Q9NR97 11/20 0.46
EP300 Q09472 5/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27977634 1.00 FGFR1 (0.48) FGFR1TLR8EP300
SCHEMBL25628523 1.00 FGFR1 (0.48) FGFR1TLR8EP300
SCHEMBL13975422 1.00 FGFR1 (0.48) FGFR1TLR8EP300
SCHEMBL27723178 1.00 FGFR1 (0.48) FGFR1TLR8EP300
SCHEMBL13261399 0.98 TLR8 (0.47) FGFR1TLR8EP300
SCHEMBL19631097 0.93 FGFR1 (0.45) FGFR1TLR8EP300
SCHEMBL2967556 0.86 FGFR1 (0.43) FGFR1EP300
SCHEMBL23343373 0.86 FGFR1 (0.44) FGFR1EP300
SCHEMBL6551980 0.84 FGFR1 (0.45) FGFR1EP300
SCHEMBL8840764 0.83 FGFR1 (0.41) FGFR1EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399355-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF Lakewood Amedex, Inc. 2023-12-14 US disclosed
US-11795192-B2 Antimicrobial compounds, compositions, and uses thereof Lakewood Amedex, Inc. (US) 2023-10-24 US disclosed
US-20230026056-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF Lakewood Amedex, Inc. 2023-01-26 US disclosed
CN-101341192-A Supramolecular polymers SECR DEFENCE (GB) 2009-01-07 CN disclosed
US-20090005519-A1 Supramolecular Polymers THE SECRETARY OF STATE FOR DEFENCE (GB) 2009-01-01 US disclosed
US-20090005519-A1 Supramolecular Polymers THE SECRETARY OF STATE FOR DEFENCE (GB) 2009-01-01 US disclosed
EP-1966283-A1 SUPRAMOLECULAR POLYMERS THE SECRETARY OF STATE FOR DEFENCE (GB) 2008-09-10 EP disclosed
WO-2007072000-A1 SUPRAMOLECULAR POLYMERS THE SECRETARY OF STATE FOR DEFENCE (GB) 2007-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230026056-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF CAT, MPO, NISCH FGFR1 4853/4885TLR8 423/4885EP300 3624/4885
US-11795192-B2 Antimicrobial compounds, compositions, and uses thereof CAT, MPO, NISCH FGFR1 4853/4885TLR8 423/4885EP300 3624/4885
US-20230399355-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF CAT, MPO, NISCH FGFR1 4853/4885TLR8 423/4885EP300 3624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.