Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 7/20 | 0.59 |
| ▸ | KDM5C | P41229 | 5/20 | 0.59 |
| ▸ | KDM5B | Q9UGL1 | 5/20 | 0.59 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.59 |
| ▸ | ALKBH5 | Q6P6C2 | 4/20 | 0.59 |
| ▸ | KDM4A | O75164 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | KDM6B | O15054 | 3/20 | 0.59 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.59 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.59 |
| ▸ | KDM5A | P29375 | 3/20 | 0.59 |
| ▸ | TET3 | O43151 | 1/20 | 0.59 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ASPH | Q12797 | 1/20 | 0.59 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.59 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.59 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.59 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19632054 | 0.84 | FTO (0.51) | FTOKDM5CKDM5BKDM4CALKBH5 | |
| SCHEMBL19632046 | 0.84 | FTO (0.54) | FTOKDM5CKDM5BKDM4CALKBH5 | |
| SCHEMBL19615962 | 0.84 | KDM4E (0.52) | FTOKDM5CKDM5BKDM4CALKBH5 | |
| SCHEMBL19615529 | 0.84 | FTO (0.54) | FTOKDM5CKDM5BKDM4CALKBH5 | |
| Hydrochloric Acid SCHEMBL19615740 | 0.82 | FTO (0.53) | FTOKDM5CKDM5BKDM4CALKBH5 | |
| SCHEMBL19615601 | 0.82 | KDM5A (0.49) | FTOKDM5CKDM5BKDM4CALKBH5 | |
| SCHEMBL19616541 | 0.81 | KDM4C (0.54) | FTOKDM5CKDM5BKDM4CALKBH5 | |
| SCHEMBL19631973 | 0.80 | FTO (0.67) | FTOKDM5CKDM5BKDM4CALKBH5 | |
| SCHEMBL19616074 | 0.79 | FTO (0.65) | FTOKDM5CKDM5BKDM4CALKBH5 | |
| SCHEMBL19632075 | 0.79 | KDM4C (0.55) | FTOKDM5CKDM5BKDM4CALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198785-A1 | OXIME DERIVATIVES USEFUL AS INHIBITORS OF HISTONE DEMETHYLASE KDM4C | IEO - ISTITUTO EUROPEO DI ONCOLOGIA S.R.L. (IT) | 2017-11-23 | — | — | WO | disclosed |