Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 7/20 | 0.67 |
| ▸ | KDM5C | P41229 | 5/20 | 0.67 |
| ▸ | KDM5B | Q9UGL1 | 5/20 | 0.67 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.67 |
| ▸ | KDM4A | O75164 | 4/20 | 0.67 |
| ▸ | ALKBH5 | Q6P6C2 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | KDM6B | O15054 | 3/20 | 0.67 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.67 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.67 |
| ▸ | KDM5A | P29375 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | TET3 | O43151 | 1/20 | 0.67 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | ASPH | Q12797 | 1/20 | 0.67 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.67 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.67 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.67 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19631951 | 0.82 | FTO (0.67) | FTOKDM5CKDM5BKDM4CKDM4A | |
| SCHEMBL19615673 | 0.81 | KDM4E (0.54) | FTOKDM5CKDM5BKDM4CKDM4A | |
| SCHEMBL72377 | 0.81 | KDM5C (1.00) | FTOKDM5CKDM5BKDM4CKDM4A | |
| SCHEMBL29382783 | 0.81 | KDM5C (1.00) | FTOKDM5CKDM5BKDM4CKDM4A | |
| SCHEMBL19631993 | 0.80 | FTO (0.59) | FTOKDM5CKDM5BKDM4CKDM4A | |
| SCHEMBL6236560 | 0.79 | FTO (0.74) | FTOKDM5CKDM5BKDM4CKDM4A | |
| Water SCHEMBL2650345 | 0.79 | KDM5C (0.96) | FTOKDM5CKDM5BKDM4CKDM4A | |
| Hydrochloric Acid SCHEMBL10778857 | 0.79 | KDM5C (0.96) | FTOKDM5CKDM5BKDM4CKDM4A | |
| SCHEMBL2276257 | 0.79 | KDM5C (0.96) | FTOKDM5CKDM5BKDM4CKDM4A | |
| SCHEMBL9585979 | 0.79 | FTO (0.96) | FTOKDM5CKDM5BKDM4CKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198785-A1 | OXIME DERIVATIVES USEFUL AS INHIBITORS OF HISTONE DEMETHYLASE KDM4C | IEO - ISTITUTO EUROPEO DI ONCOLOGIA S.R.L. (IT) | 2017-11-23 | — | — | WO | disclosed |