Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | OGA | O60502 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19615729 | 0.98 | KDM4E (0.42) | KDM4EOGACYP11B2 | |
| Hydrochloric Acid SCHEMBL19615731 | 0.98 | KDM4E (0.42) | KDM4EOGACYP11B2 | |
| SCHEMBL19632068 | 0.82 | KDM4E (0.50) | KDM4E | |
| SCHEMBL14762169 | 0.81 | ALDH1A1 (0.41) | KDM4EOGACYP11B2ACSS2 | |
| SCHEMBL30517286 | 0.81 | ALDH1A1 (0.41) | KDM4EOGACYP11B2ACSS2 | |
| SCHEMBL19632039 | 0.81 | OGA (0.33) | OGACYP11B2ACSS2 | |
| Hydrochloric Acid SCHEMBL19615613 | 0.80 | ALDH1A1 (0.40) | KDM4EOGACYP11B2ACSS2 | |
| SCHEMBL29272351 | 0.76 | KDM4E (0.49) | KDM4E | |
| SCHEMBL29878775 | 0.75 | ALDH1A1 (0.43) | KDM4E | |
| SCHEMBL9243795 | 0.74 | KDM4E (0.49) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198785-A1 | OXIME DERIVATIVES USEFUL AS INHIBITORS OF HISTONE DEMETHYLASE KDM4C | IEO - ISTITUTO EUROPEO DI ONCOLOGIA S.R.L. (IT) | 2017-11-23 | — | — | WO | disclosed |