Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344177 | 1.00 | KDM4E (0.49) | KDM4ENOS3NOS2KMT2APOLB | |
| SCHEMBL8570227 | 1.00 | KDM4E (0.49) | KDM4ENOS3NOS2KMT2APOLB | |
| SCHEMBL19632011 | 0.85 | KDM4E (0.45) | KDM4ENOS3NOS2KMT2APOLB | |
| Hydrochloric Acid SCHEMBL19615616 | 0.84 | KDM4E (0.44) | KDM4ENOS3NOS2KMT2APOLB | |
| Hydrochloric Acid SCHEMBL19615617 | 0.84 | KDM4E (0.44) | KDM4ENOS3NOS2KMT2APOLB | |
| SCHEMBL1991324 | 0.82 | NOS3 (0.52) | KDM4ENOS3NOS2KMT2APOLB | |
| SCHEMBL3719130 | 0.79 | NOS3 (0.46) | NOS3NOS2KMT2AADRB2DDR1 | |
| SCHEMBL12446917 | 0.79 | NOS3 (0.50) | NOS3NOS2KMT2APOLBADRB2 | |
| SCHEMBL13847246 | 0.79 | NOS3 (0.50) | NOS3NOS2KMT2APOLBADRB2 | |
| SCHEMBL2337914 | 0.79 | NOS3 (0.50) | NOS3NOS2KMT2APOLBADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439910-A | For applying to plants, seeds or soils | ZENECA LIMITED (GB) | 1995-08-08 | — | — | US | disclosed |
| EP-0586393-A1 | SUBSTITUTED-2-PHENYL-3-METHOXYPROPENOATES AS FUNGICIDES | ZENECA LIMITED (GB) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992018487-A1 | SUBSTITUTED-2-PHENYL-3-METHOXYPROPENOATES AS FUNGICIDES | ZENECA LIMITED (GB) | 1992-10-29 | — | — | WO | disclosed |